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Streptomyces galilaeus

Daunomydnol and its aglycone 7-Deoxydauno-mycinol aglycone Streptomyces stetfisburgensis Streptomyces coeruleorubidus Streptomyces galilaeus... [Pg.189]

By fermentation of Streptomyces galilaeus MA 144-Ml (ATCC 3113) separation of aclacinomycin A and B by column chromatography. [Pg.35]

Fujii I and Ebizuka Y (1997) Anthracycline biosynthesis in Streptomyces galilaeus. Chem Rev 97, 2511-2523. [Pg.119]

K. Raty, J. Kantola, A. Hautala, J. Hakala, K. Ylihonko, and P. Mantsala, Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster, Gene, 293 (2002) 115-122. [Pg.208]

Raty K, Kunnari T, Hakala J et al (2000) A gene cluster from Streptomyces galilaeus involved in glycosylation of aclarubicin. Mol Gen Genet 264 164-172... [Pg.141]

Raty K, Hautala A, Torkkell S et al (2002) Characterization of mutations in aclacinomycin A-non-producing Streptomyces galilaeus strains with altered glycosylation patterns. Microbiology 148 3375-3384... [Pg.141]

Streptomyces steffisburgensis Streptomyces coeruleorubidus Streptomyces galilaeus... [Pg.189]

Yoshimoto, A., Matsuzawa, Y., Oki, T., Takeuchi, T., and Umezawa, H. (1981) New anthracycline metabolites from mutant strains of Streptomyces galilaeus MA144-M1. I. Isolation and characterization of various blocked mutants. J. Antibiot. 34, 951—958. [Pg.460]

H. (1982) New anthracycline metabolites from two blocked mutants of Streptomyces galilaeus MA144-M1. J Antibiot. 35, 1641—1645. [Pg.460]

Blumauerova, M., Kralovcova, E., Mateju, J., Jizba, J., and Vanek, Z. (1979) Biotransformations of anthracyclinones in Streptomyces coeruleorubidus and Streptomyces galilaeus. Folia Microbiol. 24,117—127. [Pg.462]

Anthraqrclines without substituents in ring A are rare and not more than ten are known. 4-Deoxyauramycinone (25a) was isolated from Streptomyces galilaeus in 1983 [27,28] and re-isolated from a marine-derived Streptomyces strain [29]. Antibiotic and antitumor activities were reported, although the biological activities of the aglycones are usually neghgible. [Pg.17]

Glycosides of both subgroups have been isolated. Examples are the antibacterial 11-hydroxycinerubin A (41e) from a Streptomyces galilaeus... [Pg.28]

Ylihonko K, Hakala J, Kunnari T (1999) Hybrid anthracyclines for cancer therapy from genetically engineered Streptomyces galilaeus. WO Patent 9 958 544 (Chem Abstr 131 332095)... [Pg.68]

C42H53NO15 811.878 Anthracycline antihiotic. Isol. from Streptomyces galilaeus. Antineoplastic agent used to treat malignant hlood disorders. Shows anti-HIV activity. Yellow powder. Sol. CHCI3, EtOAc ... [Pg.6]

C41H51NO15 797.852 Prod, by Streptomyces galilaeus. Antitumour and antibacterial agent. Yellow powder. [Pg.7]

C42H53N0,6 827.878 From Streptomyces galilaeus. Antineo-plastic agent. Dark yellow powder. [Pg.7]

Biosynth. prod, of Streptomyces galilaeus. Yellow powder. Sol. MeOH, Me2CO, CHCI3 poorly sol. H2O, hexane. [Pg.7]

C41H51NO15 797.852 Anthracycline antibiotic. Numbering systems vary. Isol. from Streptomyces galilaeus (OBB-111). Active against gram-positive bacteria, mycobacteria and tumours Yellow powder. Sol. MeOH, CHCI3 poorly sol. H2O, hexane. Mp 141°. [a]o -8 (c, 0.1 in CHCI3). Vax 228 (ElWlcm 620) 258 (El%/lcm 375) 288 (ElWlcm 135) 433 (ElWlcm 200) (MeOH) (Berdy). [Pg.184]

See other pages where Streptomyces galilaeus is mentioned: [Pg.94]    [Pg.169]    [Pg.195]    [Pg.208]    [Pg.77]    [Pg.4]    [Pg.432]    [Pg.25]    [Pg.29]    [Pg.78]    [Pg.180]    [Pg.181]    [Pg.4]    [Pg.581]    [Pg.684]    [Pg.184]    [Pg.184]    [Pg.184]    [Pg.184]    [Pg.185]   
See also in sourсe #XX -- [ Pg.169 , Pg.195 ]



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