Stimulants developmental disorders

Recent open and double-blind studies indicate that methylphenidate can help a subset of autistic hyperactive children, particularly those with IQs >45, by decreasing ADHD-like symptomatology without increasing stereotypies, tics, or anxiety (Birmaher et ah, 1988 Aman et ah, 1993, 1997 Quintana et al. 1995 Handen et al., 1999). While some patients with pervasive developmental disorders (FDD) experienced adverse reactions to stimulants, the majority of them had IQs of <45 (Handen et al., 1999). 

Reductions in aggressive behavior after treatment with amphetamine and other psyehomotor stimulants are seen in children and adolescents who have been diagnosed with hyperkinesis or attention deficit disorder. There is considerable disagreement about these diagnostic categories and about whether the violent outbursts and uncontrolled episodes of aggressive behavior are limited to the early developmental period or continue into adulthood (Mendelson et al. 1971 Minde et al. 1972). 

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