Steroid alkaloids Solanum group

Tomatine, belonging to the group of solanum steroid alkaloids and having tomatidine as aglycone, is an antifungal steroidlike molecule that is one of the natural toxins in tomatoes. Tomatine is present at 36 mg per 100 g tomato. 

This second volume, which reviews the alkaloid literature from July 1970 to June 1971, approaches more closely the standard Specialist Periodical Report originally envisaged by the Chemical Society and adopts a form which, with minor variations, will very probably be followed in subsequent volumes. Once again the whole field of alkaloid chemistry has been reviewed, with the exception of the Steroidal Alkaloids of the Solanum and Veratrum Groups. The omission of these groups in the first volume was deliberate their inclusion in the second volume was intended, but proved to be impracticable, and we hope to remedy this omission in the third volume. It is fortunate, however, that this particular area can quite properly be discussed in a volume devoted to alkaloids or in one devoted to steroids and for a brief review of recent developments in this subject the reader is meanwhile referred to the Specialist Periodical Report on Terpenoids and Steroids, Volume One (Senior Reporter Dr. K. H. Overton). 

Furostanol glycosides Jurubine [(25S)-3/J-amino-26-( 8-D-glucopyranosyloxy)-5a-furostan-22a-ol] is the only compound of this group for which the structure has been elucidated. It is so far the first and only furostanol glycoside to be isolated (see steroid saponins). Enzymatic or acidic hydrolysis of the glucoside furnishes jurubidine (see Solanum steroid alkaloids) after spontaneous and stereospecific cyclization. 

Volume 10 in the series "The Alkaloids" edited by R.H.F. Manske appeared of which almost half was devoted to the steroid alkaloids of the Solanum and Veratrum groups. The remainder includes sections on Rrythro-phleum, lycopodium, benzyllsoquinollne. Indole and Taxus alkaloids. 

STEROID ALKALOIDS THE Solanum GROUP TABLE I—continued... 

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