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Sterculia urens Roxb antiviral activity

PS from terrestrial plants have also been reported as anti-CMV agents. For example, PS from three plant species, Astragalus brachycentrus D. C., Astragalus echidnaeformis Sirjaev and Sterculia urens Roxb., which are devoid of in vitro antiviral activity, were evaluated in mouse models of murine CMV infections [109], Treatment with the compounds needed to be started one day prior to virus inoculation for maximum protective benefit. Treatments starting after virus inoculation were ineffective. The mannose-specific plant PS from the orchid species Cymbidium hybrid Cym., Epipactis helleborine (L) Crantz. and Listera ovata (L.) R.Br. Svenska are potent and selective inhibitors of human CMV in vitro [110], They presumably interact at the level of virion fusion with the target cell. [Pg.405]


See also in sourсe #XX -- [ Pg.30 , Pg.405 ]

See also in sourсe #XX -- [ Pg.405 ]




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