Vomiting stem cells

Ozdemir E, Akgedik K, Akdogan S, Kansu E. The lollipop with strawberry aroma may be promising in reduction of infusion-related nausea and vomiting during the infusion of cryopreserved peripheral blood stem cells. Biol Blood Marrow Transplant 2008 14(12) 1425-8. 

Patients (n = 23) who had undergone allogeneic haematopoietic stem cell transplantation were tested for efficacy and side effects resulting from deferasirox treatment due to hyperferritinemia [25 ]. The most common side effect was nausea and vomiting (n=3). 

Loss of hair results from injury to hair follicles gastrointestinal disturbances, such as diarrhea, from inadequate replacement of enterocytes whose life span is limited to a few days nausea and vomiting from stimulation of area postrema chemoreceptors (p. 330) and lowered resistance to infection from weakening of the immune system (p. 300). In addition, cytostatics cause bone marrow depression. Resupply of blood cells depends on the mitotic activity of bone marrow stem and daughter cells. When myeloid proliferation is arrested, the short-lived granulocytes are the first to be affected (neutropenia), then blood platelets (thrombopenia) and, finally, Liillmann, Color Atlas of Pharmacology... 

Annona senegalensis stem bark is used for the treatment of hysteria and a constituent of its root bark has been found efiective for treating cancer using sarcoma 180 ascites cells (75). The bark and root are used in the treatment of sexually transmitted diseases (18). The root bark contains cardenolides, glycosides and saponins. The stem bark contains anthranoids, cardenolides, glycosides saponins and terpenoids (50,18). Its fraits are edible and are taken for diarrhoea, dysentery and vomiting (23,33). 

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