Statutory mandates

Risk Estimation. As mentioned above, chronic risk is expressed as a probability of occurrence per year or per lifetime of some adverse consequence caused by exposure to the pollutant. Statutory mandates have focused on human health effects as the primary expression of chronic risks. The basis of the risk calculation is the dose/response curve that relates the adverse effect to the amount or rate of a chemical taken in to the subject. Because of regulatory emphasis of cancer, most of the work devoted to the deviation of dose/response curves has been concerned with the probability of appearance of a tumor as the adverse effect. 

As expressed in Equation 4-1, the spatial and temporal distributions of pollutants must be known to assess their damage to receptors. Traditionally, monitoring station measurements are used to estimate the concentrations for entire regions. Statutory mandates, however, require... 

Motivated by statutory mandates for environmental evaluation of transportation systems. Darling solicited information from each originator of an air pollution model by a questionnaire advertised in the Commerce... 

Fegal/regulatory authority and structures and procedures providing for post- and preapproval Appropriate statutory mandate and jurisdiction Ability to issue and update binding requirements on cGMPs and guidance documents... 

The FDA is announcing the Agency s policy on the development and use of standards with respect to international harmonization of regulatory requirements and guidelines. Specifically, the policy is intended to address the conditions under which the FDA plans to participate with standards bodies outside of the FDA, domestic or international, in the development of standards applicable to products regulated by the FDA. The policy also covers the conditions under which the FDA intends to use the resultant standards, or other available domestic or international standards, in fulfilling its statutory mandates for safeguarding the public health. 

Statutory Mandates for FDA-Regulated Products. The FDA is the principal regulatory agency within the Public Health Service (PHS). The Agency... 

The proposed NCP recognizes the statutory mandate in Section 105(8) to develop risk assessment criteria and a National Priority List by limiting "remedial" actions to releases on the National Priority List ( 300.67(a)). This will put teeth in the mandate of Section 105(8) and will assure the importance of the risk analy-sis/prioritization process. 

Statutory mandates that require automatic fire detection and alarm systems, as well as automatic sprinkler systems, will help reduce the potential damage from an incendiary fire... 

The disclosures by Strauss and Murray angered not only Anderson but the other members of the Joint Committee, who jealously guarded their statutory mandate to be kept "fully and currently informed" on atomic matters. In this case the Joint Committee had received no report on the Safeguards Committee s conclusions. It was also annoyed that Murray had given the information, not to the Joint Committee, but to a House subcommittee. 

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