Stability measurements

Because these stability measurements pertain to the gas phase, it is important to consider the effects that solvation might have on the structure-stability relationships. Hydride affinity values based on solution measurements can be derived from thermodynamic cycles that relate hydrocarbon p T, bond dissociation energy and electrochemical potentials. The hydride affinity, AG, for the reaction... 

Fig. 3.1.6 Effects of pH on the activity and stability of Cypridina luciferase (solid lines) and the quantum yield of Cypridina luciferin (dashed line). In the measurements of activity and quantum yield, luciferin (1 pg/ml) was luminesced in the presence of luciferase (a trace amount for the activity measurement 20 pg/ml for the quantum yield) in 20 mM buffer solutions of various pH containing 0.1M NaCl, at 20°C. In the stability measurement, luciferase (a trace amount) was left standing in 0.1 ml of the buffer solutions of various pH for 30 min at 20°C, then the activity was measured by adding 1 ml of 50 mM sodium phosphate buffer, pH 6.5, containing 0.1 M NaCl and 1 pg of luciferin, at 20°C. The activity and stability data are taken from Shimomura et al., 1961, with permission from John Wiley 8c Sons Ltd.

XYZCELL.dat Section 2.4 Fifty six stability measurements were taken on a series of product batches during a program that included storage at 4°, 25°, 31°, 40°, and 41°C and sampling at 0, 1, 3, resp. 6 months the assay of the drug substance is given in %-nominal, and the concentrations... 

To measure the influence of the mixing procedure on the sedimentation and turbidity (1) the stirrer speed, vR rpm, (2) the time of polymer addition, tz[min], and (3) the time of stirring after addition of the polymer, tN[min], were varied. Two polymer coverages, 0 0.2 and 6 1.0, at three pH-values, pH A.7, pH 3.2 and pH 2.3 (the latter is close to the isoelectric point) were selected for the stability measurements. Fig. 2 shows the dependence of the three stability characterizing parameters T(l )Ere ... 

Nakagami, T. and Yokota, T. (1983). Estimation of crosslink-formation among wood components by dimensional stability measurements. Mokuzai Gakkaishi, 29(3), 240-247. 

Powell, K.D. Wales, T.E. Fitzgerald, M.C. Thermodynamic stability measurements on multimeric proteins using a new H/D exchange-and matrix-assisted laser desorption/ ionization (MALDl) mass spectrometry-based method. Protein Sci. 2002, 11, 841-851. 

Another step of the production process, equally important to the homogeneity measurement, is the stability measurement. The measurement method requirements are the same as those for the measurement of homogeneity for the same reasons. At this stage there are two additional requirements. The measurements are performed on samples stored at different temperatures, in order to determine the appropriate storage temperature and at different times, in order to determine the lifetime of the certified reference material. 

Zidovudine-treated, HiV-infected and cancer patients - Measure hemoglobin once a week until it is stabilized measure periodically thereafter. 

Melton, S. L., Jafar, S., Sykes, D., and Trigiano, M. K. (1994). Review of stability measurements for frying oils and fried food flavor. ]. Am. Oils Chem. Soc. 71, 1301-1308. 

Li-peroxo transition metal complexes, 1060 Conductivity, oxidation stability measurement, 664... 

Cutinase AOT-isooctane Spin-label at the active site activity and stability measurements (w,) [23]... 

Activity and stability measurements of the enzyme entrapped inside POPC vesicles against externally added Bz-Tyr-pNA. No activity against the larger substrate Suc-Ala-Ala-Pro-Phe-pNA or casein. Inhibition of externally present enzyme by an inhibitor protein. 

Improved heat-resistant UV compositions for optical fiber applications These compositions are nonurethane UV cure compositions that have neither carbamate moieties nor long-chain poly(alkylene oxide) soft segments and exhibit inherently better thermal stability measured by thermogravimetric analysis (TGA) than typical coatings for optical fibers based on urethane acrylate oligomers. 

Figure 4.2 Stability measurement setup for three-terminal regulator.

Foam Stability Measurements. The average lifetime (LF) is a property of bulk foams that is useful in ranking foams in order of stability. LF is defined as the area under the drainage profile divided by the initial foam height The apparatus used to determine these drainage profiles is shown in Fig. 9. 

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