Spray drying mathematical models

A Negiz, ES Lagergren, and A Cinar. Mathematical models for concurrent spray drying. Ind. Engg. Chem. Research, 34 3289-3302, 1995. 

Various mathematical models and simulation tools have been developed to predict temperature-time and moisturetime profiles and morphological changes of droplets inside a spray dryer. These simulations are usually validated using data obtained from SDD experiments (explained in Section 49.7.1.4). The currently available models applied to predict the drying kinetics of droplets can be placed into three categories ... 

Huang L., Mujumdar A.S., 2005, Development of a new innovative conceptual design for horizontal spray dryer via mathematical modeling. Drying Technology, 23, 1169-1187. 

Recently SFD has attracted the attention of formulation scientists. Spray-freeze drying of aqueous solutions of pure proteins or protein/sugar combinations (Maa et al. [5]) produced larger, more porous particles than those prepared by SD. When the modeling of SFD process is concerned, a mathematical model based on a steady-state heat-transfer condition has been derived by Maa and Prestrelski [6] that can be used to estimate the freezing time in liquid nitrogen, for instance. 

Structure Formation within Spray-Dried Droplets Mathematical Modelling of Spray Polymerisation... 

Spray polymerisation can be seen as an extension of spray drying in which the solid is formed by polymerisation reactions. Literature models of spray polymerisation treat droplets as fully mixed. Mathematical models accounting for spatial... 

A Mathematical Model of Spray Polymerisation and Reactive Spray Drying... 

We begin this chapter with a comparison of the mechanisms responsible for mass and heat transfer. The mathematical similarities suggested by these mechanisms are discussed in Section 21.1, and the physical parallels are explored in Section 21.2. The similar mechanisms of mass and heat transfer are the basis for the analysis of drying, both of solids and of sprayed suspensions. However, the detailed models differ, as shown by the examples in Section 21.3. In Section 21.4, we outline cooling-tower design as an example based on mass and heat transfer coefficients. Finally, in Section 21.5, we describe thermal diffusion and effusion. 

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