Spleen tubercles

Table 33 showed that of the ten animals in the untreated group, eight developed minute tubercles in the liver, five in the spleen and lungs, and nine in the peritoneum and intestines microscopic necrosis suggestive of caseation was found in the liver of three animals and in the spleen, peritoneum, and intestine each in one animal. Smears of acid-fast bac-... 

A single injection of cord factor, which by itself has no lasting deleterious effects, causes tuberculous infections to progress more rapidly than they otherwise would thus, mice receiving an injection of cord factor prior to infection die sooner than controls their lungs, livers, and spleens contain a greater number of viable tubercle bacilli than do the organs of control animals. 

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