Spinal trigeminal nucleus

X3 NM 002559 Dorsal root ganglion, superficial dorsal horn of spinal cord, a subset of small-diameter sensory neurons, nucleus of the solitary tract, spinal trigeminal nucleus (important for peripheral pain)... 

Extrasynaptic in hippocampus, cerebral cortex, and olfactory bulb synaptic and extrasynaptic in spinal trigeminal nucleus and superior olivary nucleus... 

HT3 receptors are located exclusively on neurons and are widely distributed throughout the peripheral and central nervous systems. In the periphery, 5-HT3 receptors are found on autonomic, sensory, and enteric neurons (Fozard 1984). In the central nervous system, 5-HT3 receptors are labeled in cortex, hippocampus, caudate hypothalamus, brain stem, midbrain, and cerebellum, with the highest density in discrete nuclei of the lower brain stem (e.g., dorsal vagal complex and spinal trigeminal nucleus), the area postrema, and substantia gelatinosa at all levels of the spinal cord (Palacios et al. 1991 Waeber et al. 1989). 

C. S. Effect of baclofen enantiomorphs on the spinal trigeminal nucleus and steric similarites of carbamazepine. Pharmacology 1983, 27, 85-94. 

Fromm GH, Terrence CF, Chattha AS, Glass JD. Baclofen in trigeminal neuralgia its effect on the spinal trigeminal nucleus a pilot study. Arch Neurol 1980 37(12) 768-71. 

Refer to Tracey and Waite (1995) and Waite and Tracey (1995) for a general description of the somatosensory system. The general basis of delineation of these structures is described in Paxinos and Watson (1996). However, we followed Marfurt and Rajchert (1991) for the borders of the spinal trigeminal nucleus. 

Iliakis B, Anderson NL, Irish PS, Henry MA, Westrum LE (1996) Electron microscopy of immunoreactivity patterns for glutamate and y-aminobutyric acid in synaptic glomeruli of the feline spinal trigeminal nucleus (subnucleus caudalis). J Comp Neurol 566 465-477. 

Magnusson KR, Larson AA, Madl JE, Altschuler RA, Beitz AJ (1986) Co-localization of fixative-modified glutamate and glutaminase in neurons of the spinal trigeminal nucleus of the rat an immunohistochemical and immunoradiochemical analysis. J Comp Neurol 247 477-490. 

Branching was found of axon collaterals from single cells in the spinal trigeminal nucleus between pairs of patches with the same receptive fields located on the same or on a different folium, or between patches located in vermis and hemisphere (Woolston et al., 1981). Projections from the somatosensory cortex and the superior colliculus, moreover, were found to conform to the patchy mosaic of projections of the periphery to the granular layer of the rat cerebellar hemisphere (Bower et al., 1981 Kassel, 1980). 

Helke CJ, Jacobowitz DM, Thoa NB (1981) Capsaicin and potassium evoked substance P release from the nucleus tractus soUtarius and spinal trigeminal nucleus in vitro. Life Sci 29 1779-1785 Honda H, Takahama K, Kawaguchi T, Fuchikami J, Kai H, Miyata T (1990) Involvement of N-methyl-D-aspartic acid (NMDA) receptor in the central mechanism of cough reflex. Jpn J Pharmacol 52(Suppl. 1) 308... 

Macon, J. B., 1979, Deafferentation hyperactivity in the monkey spinal trigeminal nucleus neuronal responses to amino acid iontophoresis. Brain Res. 161 549-554. 

Analgesia (Head) Substantia gelatinosa of spinal trigeminal nucleus... 

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