Spices curcumin

Lim GP, Chu T, Yang F, Beech W, Frautschy SA, Cole GM. 2001. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci 21 8370-8377. 

The pigment mixture from turmeric is used to dye textiles (yellow to brown, cotton, wool, and silk) and to color certain foodstuffs. Curcumin is an important constituent of Indian curry spice. Curcumin inhibits lipid peroxidation and has antibacterial activity. It inhibits activation of transcription factor NFxB (relevant for signal transduction, septic shock, inflarrunatory diseases). ... 

Lim, G.P., Chu, T., Yang, F., et al. The Curry Spice Curcumin Reduces Oxidative Damage and Amyloid Pathology in an Alzheimer Transgenic Mouse. J. Neurosci. 21, 8370-8377 (2001)... 

Balasubramanian K. Molecular orbital basis for yellow curry spice curcumin s prevention of Alzheimer s disease. Journal of Agricultural and Food Chemistry, 54 3512-3520 (2006). 

Curcumin (E100). Curcumin is obtained from the spice turmeric, which comes from the plant Curcuma longa, of the ginger family. Curcumin is obtained by extraction from the plant to give a deodorised product. 

The importance of NF-kB to inflammation, apoptosis resistance and tumour progression has resulted in the development of unique NF-kB inhibitors as part of cancer therapeutic regimens for GI and other cancers. Efforts are also being made to understand the efficacy of using natural substances obtained from plants, such as feverfew (e.g. parthenolide), bee glue (e.g. caffeic acid phenylethyl ester), tea (e.g. EGCG), spices (e.g. curcumin from turmeric) and mulberry figs (e.g. morin, a flavone) for the prevention both of persistent NF-kB activation and of the development of inflammatory pre-neoplastic lesions. 

Curcumin (16) is a polyphenolic compound derived naturally from the plant Curcuma longa also known as turmeric (Haldi). It is the primary source of the distinctive bright yellow color of the spice commonly used in the preparation of curries. Originating in India, turmeric was probably cultivated initially as a dye, and later used in cosmetics and foods. It has... 

Those that have been identified in recent times include flavonoids,212-214 aurothiomalate,215 hydrangenol,216 occurring in the leaves of Hydrangea, tannins,217 derivatives of tranilast,218 curcumin,219 an extract of the spice turmeric, glycyrrhizin,220 found in the roots and rhizomes of licorice (Glycyrrhiza glabra), used as an effective antiinflamatory agent in Chinese medicine. 

Turmeric. Turmeric (Curcuma longa) is a member of the ginger family and has traditionally been used as a spice that adds flavor and color to mustard and curry powder. It comes from India and southern Asia, where the stalk of the plant is scalded, dried, and made into a powder, tablet, capsule, ointment, cream, lotion, or tea. The best-characterized ingredient of turmeric is a substance called curcumin. Curcumin is an antioxidant that also causes certain cells in the body to release steroids such as cortisol, which help fight inflammation... 

Janssen, A. and Gole, T. (1 984) Thin-layer chromatographic determination of curcumine (turmeric) in spices. Chromatographia 18, 546-549. 

With regard to turmeric, cited earlier as an immune system enhancement agent, and a spice used in curry, curcumin (or turmeric), the bright yellow active ingredient. 

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