Spectra subgroup

EHEC are the pathogenic subgroup of Stx-producing E. coli (STEC). Acute hemorrhagic colitis has been associated mainly with the 0157 H7 serotype. This serotype has been responsible for larger outbreaks of infection, has higher rates of complications, and appears to be more pathogenic than non-EHEC STEC strains. The spectrum of disease associated with E. coli 0157 H7 includes bloody diarrhea, which is seen in as many as 95% of patients, nonbloody diarrhea, hemolytic-uremic syndrome (HUS), and thrombotic thrombocytopenic purpura. 

A recently characterized single-domain copper protein, auracyanin (Trost et al., 1988), is a dimeric protein which has a visible spectrum more like that of the A. faecalis cupredoxin (pseudoazurin, subgroup II see Table II) than that of either azurin or plastocyanin, but, because of its cysteine content and rhombic EPR, it has been put in the other class in Table II. 

Figure 9.18—NMR spectra nomenclature. The H spectrum of 3-chIoro-4-methylpropiophenone can be considered as a group of independent signals resulting from subgroups that are easily identified.

Explore the effect of variability in study quality and other characteristics (setting, type of population, disease spectrum, etc.) on estimates of accuracy, using subgroup analysis or modeling. 

There are a few new reports of the occurrence of the known alkaloids 235-237 in this subgroup, and six new ones have been isolated. These include jasminiflorine (238), a constituent of the leaves of K. jasminiflora (172,179), whose structure as 12-methoxyfruticosine was deduced by analysis of its proton NMR spectrum. 

The mechanisms of action of penicillins, the bacterial modes of resistance to penicillins, the penicillin subgroups, their biodisposition, and adverse affects are provided. The subgroups discussed are the penicillins that are p-lactamase susceptible with a narrow spectrum of activity, p-lactamase-resistant penicillins having a very narrow spectrum of activity, and J3-lactamase—susceptible penicillins with a i wider spectrum of activity. The common penicillins and their susceptible organisms are listed for each I subgroup. 

Subgroups and Antimicrobial Activity Beta-Lactamase-Susceptible and Narrow Spectrum... 

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