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Some Important Psychotropic Drug Interactions

Tricyclic antidepressants + fluoxetine, paroxetine or sertraline — increased pharmacological and toxicological effects of the tricyclic due to decreased hepatic metabolism. This is a potentially hazardous combination. [Pg.459]

Tricyclic antidepressants + MAOIs — stroke, hyperpyrexia and convulsions can occur. Potentially a hazardous combination. [Pg.459]

Tricyclic antidepressants + directly acting sympathomimetic amines (e.g. noradrenaline, adrenaline) — hypertension and arrhythmias due to enhancement of the sympathomimetic effects. [Pg.459]

Tricyclic antidepressants + phenothiazines — additive anticholinergic effects that can cause psychosis and agitation. [Pg.459]

Tricyclic antidepressants + phenytoin — reduction in phenytoin metabolism can increase phenytoin toxicity. [Pg.459]

Appendix 1 Some Important Psychotropic Drug Interactions... [Pg.459]

See other pages where Some Important Psychotropic Drug Interactions is mentioned: [Pg.461]    [Pg.461]    [Pg.191]    [Pg.31]    [Pg.114]    [Pg.186]    [Pg.31]    [Pg.114]    [Pg.505]    [Pg.282]    [Pg.193]   


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