Soluble collagens and

Piez, K. A. Soluble collagen and the components resulting from its denaturation. In ... 

Nikkari and Kulonen (1962) noted that acid-soluble lathyritic collagen exhibited an elevated a/jS ratio only when a prior NaCl extraction was omitted. Lathyrism, therefore, only causes an increased amount of salt-soluble collagen and does not affect any acid-soluble collagen that may already be present. 

J4. Jasin, H. E., and Ziff, M., Relationship between soluble collagen and urinary hydroxyproline in the lathyritic rat. Proc. Soc. ExpU. Biol. Med. 110, 837-841 (1962). 

Most proteins and protein derivatives for cosmetic use (with the significant exception of soluble collagen and enzymes) maintain little of the spatial architecture of the source proteins, and generally, in the view of their cosmetic properties, the conformational aspects of these molecules have little practical relevance. 

Only a few studies have been concerned with the percutaneous absorption of protein ingredients from cosmetic products and some controversial results have ensued. Most of these works dealt with the potential absorption of soluble collagen and were based on simple application models and selective detection of the exogenous protein radiolabeled with or (74,75). 

Below we will describe methods for isolation of both insoluble and soluble collagen and typical characterization profiles of tliese materials as well as methods used to process collagen into a variety of shapes and end-products. 

As indicated above, collagen exists in fibrous form in tissues. However, varj ing amounts of fibrous collagen will dissolve in cold acidic or near neutral buffers or even water. This material is referred to as soluble collagen and usually repi sents only a small fraction of the tot collagen present in any given ti ue. However, )luble coils en has provided the sample used for mc t studio concerned wuth the chemistry of colleen and col-... 

Chem. Descrip. Macromolecular soluble collagen and cocoamphoacetate Uses Detergent for sensitive skin, personal hygiene prods., shampoos for damaged hair, detergent tissues Features Very mild Collagen LSS Complex [Kelisema Sri]... 

Chem. Descrip. Macromolecular soluble collagen and sodium lauryl sulfate Uses Surfactant, foaming agent for bubble baths, shampoos, Iiq. soaps Features Mild high foaming Colonial 1240 Slurry [Colonial Chem.)... 

Acid-soluble collagen and the homopolymers of a number of a-amino acids were obtained from the Sigma Chemical Co., St. Louis, Missouri, and used without further purification. 

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