Solid-state chemistry, topochemical

Short-lived organic radicals, electron spin resonance studies of, 5, 53 Small-ring hydrocarbons, gas-phase pyrolysis of, 4, 147 Solid state, tautomerism in the, 32, 129 Solid-state chemistry, topochemical phenomena in, 15, 63 Solids, organic, electrical conduction in, 16, 159 Solutions, reactions in, entropies of activation and mechanisms, 1, 1 Solvation and protonation in strong aqueous acids, 13, 83 Solvent effects, reaction coordinates, and reorganization energies on nucleophilic substitution reactions in aqueous solution, 38, 161 Solvent, protic and dipolar aprotic, rates of bimolecular substitution-reactions in,... 

Solid state, tautomerism in the, 32, 129 Solid-state chemistry, topochemical phenomena in, 15, 63 Solids, organic, electrical conduction in,... 

Tetrahedral intermediates, derived from carboxylic acids, spectroscopic detection and the investigation of their properties, 21, 37 Topochemical phenomena in solid-state chemistry, 15, 63 Transition state structure, crystallographic approaches to, 29, 87 Transition state structure, in solution, effective charge and, 27, 1 Transition state structure, secondary deuterium isotope effects and, 31, 143 Transition states, structure in solution, cross-interaction constants and, 27, 57 Transition states, the stabilization of by cyclodextrins and other catalysts, 29, 1 Transition states, theory revisited, 28, 139... 

In 1975, Cohen introduced the concept of the reaction cavity in solid state chemistry (2. The reaction cavity was defined as the space occupied by the reacting species and bounded by the surrounding, stationary molecules. Cohen viewed the topochemical principle as resulting from the preference for chemical processes to occur with minimal distortion of the reaction cavity, either in the formation of voids within it or extrusions from it (Figure 1). 

A great deal of solid state chemistry has been carried out and understood using these topochemical principles (Schmidt 1971 Thomas et al. 1977 Lahav et al. 1979 ... 

Thomas, J. M., Morsi, S. E. and Desvergne, J. P. (1977). Topochemical phenomena in organic solid-state chemistry. Arfv. Phys. Org. Chem., 15, 63-151. [235] Thompson, K. C. (2000). Pharmaceutical applications of calorimetric measurements in the new millenium. Thermochim. Acta, 355, 83-7. [250]... 

Theocharis, C. R., and Jones, W. Topotactic and topochemical photodimerization of benzylidenecyclopentanones. In Organic Solid State Chemistry. (Ed., Desiraju, G. R.) Ch. 2., pp. 47-68. Elsevier Amsterdam, Oxford, New York, Tokyo (1987). 

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