Software used in the analysis of electron micrographs

Packages that allow a complete analysis of images are well established but each package was originally developed for a specific group of specimens. The MRC 

MOLREP, EMfit are packages that may be used for the interpretation and objective fitting of data. O and PyMOL are used mainly for manual fitting and inspection of data. 

We have discussed the need for examining specimens close to their native state by cryo-EM and shown that high-resolution, hut noisy, images result. After data analysis and image enhancement by computer processing, a three-dimensional reconstruction can he determined. We now present that state of the art with some of the highlights that have been achieved to date. 

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