Soft-tissue sarcoma, risk from exposure

The hypothesis that phenoxy herbicides are a cause of soft tissue sarcoma (STS) also commenced in Sweden. Three case-control studies conducted by the same investigators reported relative risks of 3.3 to 5.7 for such an association (Table V) (42-44 ). However, as with malignant lymphoma, it is difficult to explain such dramatic risks associated with short term exposures. Moreover, Wiklund and Holm (45) found no overall risk increase from STS among Swedish agriculture and forestry workers (RR—0.9 95% Cl 0.8-1.0). 

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