Sodium perborate periodates

In a 1-1. three-necked round-bottomed flask equipped with an eflicient stirrer, a reflux condenser, and a thermometer (Note 1) are placed 500 ml. of glacial acetic acid (Note 2), 29.0 g. (0.19 mole) of -aminoacetanilide (Note 3), 40 g. (0.26 mole) of sodium perborate tetrahydrate, and 10 g. (0.16 mole) of boric acid. The mixture is heated with stirring to 50-60° and held at this temperature for 6 hours. Initially the solids dissolve but, after heating for approximately 40 minutes, the product begins to separate. At the end of the reaction period, the mixture is cooled to room temperature and the yellow product is collected on a Buchner funnel. It is washed with water until the washings are neutral to pH paper (Note 4) and then dried in an oven at 110°. The yield of 4,4 -bis(acetamido)a2obenzene, m.p. 288-293° (dec.), is 16.5 g. (57.7%). It is used as such for the hydrolysis step (Note 5). 

Sodium N-methylanilide-Hexamethyl-phosphoric triamide, 367-368 Sodium methylselenolate, 368 Sodium perborate, 239 Sodium periodate, 93 Sodium permanganate monohydrate,... 

Sodium mtrite-CF,COjH-DMSO, 386-387 Sodium perborate, 387 Sodium periodate, 358 Sodium-potassium alloy, 436 Sodium sulfite, 387 Sodium telluride, 388 Sodium thiophenoxide, 317 Sodium trichloroacetate, 388-389 Sodium trithiocarbonate, 389 Spinachrome D, 342 Spiro[2.5]octadiene-3-one, 18 S-Protein, 5... 

The phase-transfer-assisted permanganate oxidation of alkynes and alkenes has been reviewed. Terminal and internal alkynes are oxidized to 1,2-dicarbonyl compounds by the combined action of diphenyl disulphide, ammonium peroxidisulphate and water or by sodium periodate in the presence of ruthenium dioxide (equation 34). Other reagents for the conversion of acetylenes into 1,2-dicarbonyl compounds are hydrogen peroxide in the presence of (2,6-dicarboxylatopyridine)iron(II), the complex oxo(A, A -ethylenebissalicylideneiminato)chromium(V) trifluoromethanesulphonate (216)and ruthenium tetroxide as a mediator in electrooxidation. l-Acetoxyalkan-2-ones 217 are obtained by the oxidation of terminal acetylenes with sodium perborate and mercury(II) acetate in acetic acid ". Terminal alkynes give a-ketoaldehydes 218 on treatment with dilute hydrogen peroxide, combined with mercury(II) acetate and sodium molybdate or sodium tungstate under phase-transfer conditions. ... 

A modification of this method consists of the oxidative diacetoxylation of iodoarenes in acetic or trifluoroacetic acid using appropriate oxidants, such as periodates [149-151], chromium(VI) oxide [152], sodium percarbonate [153], m-chloroperoxybenzoic acid (mCPBA) [130, 154-158], potassium peroxodisulfate [159,160], HaOa-urea [161], Selectfluor [33] and sodium perborate [132]. The oxidation of iodoarenes with sodium perborate in acetic acid at 40 °C is probably the most general procedure that has been used for the small-scale preparation of numerous (diacetoxyiodo)-substituted arenes and hetarenes (Scheme 2.14) [132,133,162-166]. For example, the chiral diacetate 31 and several analogous... 

Oxidizers Peroxide, sodium chlorite, sodium hypochlorite Percarbonate, perborate, periodate, air... 

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