Sodium L-glutamate

Water-insoluble PEC were prepared by mixing oppositely charged polyelectrolytes, e.g. DEAE dextran with CMD [340,341], sodium dextran sulfate, poly(styrene sulfonate) (NaSS) [342], poly(sodium L-glutamate) (PSLG), poly(vinyl alcohol)sulfate [343], or potassium metaphosphate (MPK) [240]. They are useful as membranes or in biomedical applications [343,344]. 

Lucas, D.R., and Newhouse, IP. 1957. The toxic effect of sodium L-glutamate on the inner layers of the retina. AMAArch Ophthalmol 58, 193-201. 

Monosodium L-glutamate Monosodium L-glutamate monohydrate Sodium glutamate (INCI) Sodium L-glutamate Sodium hydrogen giutamate... 

Monosodium L-glutamate [142-47-2] C HgNO Na H20 (mol wt 187.13) crystallizes from aqueous solution at room temperature as rhombic prisms. Its stmcture, as deterrnined by x-ray crystallography (6), indicates that the sodium ions are coordinated octahedraHy by four (3a and ly) carboxyl oxygen atoms and two water molecules as follows ... 

C), the yield of more than 90% purity L-glutamic acid crystals is very high. The glutamic acid crystals appear as both the metastable a- and stable P-forms. The a-form consists of prismatic crystals which are easy to filter, whereas the P-form needle crystals are difficult to filter. Control of crystallisation conditions of a-crystals are requited (13). The cmde L-glutamic acid crystals are suspended ia water and neutralized with caustic soda or sodium hydroxide. The solution is decolorized with activated carbon to produce a transparent solution and MSG is crystallized under reduced pressure. 

Arninobenzoyl-L-glutarnic acid (12) is obtained by condensation of -nitrobenzoyl chloride [122-04-3] (18) with L-glutamic acid [56-86-0] (19) under Schotten-Baumann conditions. This is followed by reduction of the nitro group with either sodium hydrogen sulfide (29) or by electrochemical methods (30). 

Another viable method for the synthesis of L-foUc acid (1) starts from 6-formylpterin (23). The diester of L-glutamic acid (24) is condensed with 6-formylpterin (23). Reduction of the Schiff base with sodium borohydride is followed by hydrolysis to yield L-foUc acid (37). 

Sodium poly(a-L-glutamate). It was washed with acetone, dried, dissolved in water and ppted with isopropanol at 5°. Impurities and low molecular weight fractions were removed by dialysis of the aqueous solution for 50h, followed by ultrafiltration through a filter impermeable to polymers of molecular weights greater the 10. The polymer was recovered by freeze-drying. [Mori et al. J Chem Soc, Faraday Trans I 2583 1978.]... 

Methohexital sodium Diethyl-p-methylaminobenzoyl-L-glutamate Methotrexate... 

Kanner, B. I. and Bendahan, A. (1982) Binding order of substrates to the sodium and potassium ion coupled L-glutamic acid transporter from rat brain. Biochemistry 21,6327-6330. 

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