Sodium hydrogen carbonate. See

Sodium hydrogen carbonate See Sodium hydrogen carbonate Carbon, Water... 

See Sodium hydrogenated taiiow glutamate Sodium hydrogen carbonate. See Sodium bicarbonate... 

See baking powder for sodium hydrogen carbonate. See hardness in water for other hydrogencarbonates. 

To absolution of 1.00 mol of ethyl lithium in 800-900 ml of diethyl ether (see Chapter II, Exp. 1) was added, with cooling between -20 and -10°C, 0.50 nol of dry propargyl alcohol, dissolved in 100 ml of diethyl ether. Subsequently 1.1 mol of trimethylchlorosilane was introduced over a period of 25 min with cooling between -15 and +5°C. After stirring for an additional 2 h at about 30°C the suspension was poured into a solution of 30 g of acetic acid in 150 ml of water. After stirring for 1 h at room temperature the layers were separated and the aqueous layer v/as extracted four times with diethyl ether. The combined ethereal solutions were washed with sodium hydrogen carbonate solution in order to neutralize acetic acid, and were then dried over magnesium sulfate. The diethyl ether was removed by evaporation in a water-pump vacuum and the residue distilled... 

Baddeleyite, see Zirconium(IV) oxide Baking soda, see Sodium hydrogen carbonate Barite (barytes), see Barium sulfate... 

A novel method of opening of oxiranes involves the use of (chlo-romethylene)dimethyliminium chloride (39) [see Section II,2c p. 250], monochlorodeoxy or dichlorodideoxy derivatives are obtained, depending upon the reaction conditions employed.83 Thus, methyl 2,3-anhydro-4,6-0-benzylidene-a-D-allopyranoside (110) reacts with 39 in 1,1,2,2-tetrachloroethane at room temperature to give, upon hydrolysis of the primary adduct 111 with an aqueous solution of sodium hydrogen carbonate, methyl 4,6-0-benzylidene-2-chloro-2-deoxy-3-0-formyl-a-D-altropyranoside (112). If a solution of 39 and 110 in 1,1,2,2-tetrachloroethane is heated at reflux temperature, methyl 3,4-0-benzylidene-2,6-dichloro-2,6-dideoxy-o -D-altropyrano-side (113) is obtained in high yield the n.m.r. spectrum of 113, like that of 47 (see Section II, 2c p. 250), showed the presence of two diastereoisomers which differed in the configuration of the benzyl-idene-acetal carbon atom. 

Method B.104 In a 1-litre flask equipped with a condenser, a thermometer and a dropping funnel is placed 0.3 mol of lithium aluminium hydride (CAUTION, see Section 4.2.49, p. 445) in dry ether (300 ml). A nitrogen atmosphere is maintained throughout the reaction. To this stirred solution 0.45 mol of ethyl acetate is added over a period of 75 minutes maintaining the temperature at 3-7 °C. The reaction is stirred for an additional 30 minutes. To this solution at —10 °C is added 29.1 g (0.3 mol) of hexanenitrile in 5 minutes. The reaction temperature rises to 12°C in 10 minutes with the formation of a viscous solution. It is allowed to stir for another 50 minutes at 3 °C. The reaction mixture is decomposed by the addition of 300 ml of 2.5 m sulphuric acid. The ether layer is separated and the aqueous layer is extracted with ether. The combined ether extracts are washed with sodium hydrogen carbonate solution and water and dried over anhydrous sodium sulphate (1). 

Phenols may be separated from acids (for example, o-cresol from benzoic acid) by a dilute solution of sodium hydrogen carbonate the weakly acidic phenols (and also ends) are not converted into salts by this reagent and may be removed by ether extraction or by other means the acids pass into solution as the sodium salts and may be recovered after acidification. For experimental details see Sections 2.22 and 9.6.17, p. 1266. 

Miscellaneous tests. Test the solubility behaviour of 0.5-1 g of the mixture to 5 per cent sodium hydroxide solution, 5 per cent sodium hydrogen carbonate solution and to 5 per cent hydrochloric acid (for details, see under Liquid mixtures). 

Wash chloroform extract with water, sodium hydrogen carbonate, and again with water. Dry chloroform solution with anhydrous sodium sulfate, evaporate and isolate p-anomer by crystallization or perform flash chromatography to separate a- from p-anomer (see Note 6). 

Fuchsitt test Dilute solutions of triphenylmethane dyestuffs, such as fuchsin (for formula, see Section IV. 15, reaction 9) and malachite green, are immediately decolourized by neutral sulphites. Sulphur dioxide also decolourizes fuchsin solution, but the reaction is not quite complete nevertheless it is a very useful test for sulphur and acid sulphites carbon dioxide does not interfere, but nitrogen dioxide does. If the test solution is acid, it should preferably be just neutralized with sodium hydrogen carbonate. Thiosulphates do not interfere but sulphides, polysulphides, and free alkali do. Zinc, lead, and cadmium salts reduce the sensitivity of the test, hence the interference of sulphides cannot be obviated by the addition of these salts. 

In 1968 Miller and Stirling showed that the 2-tosylethyl ester function (abbreviated TSE) underwent easy base-catalysed elimination in the presence of 1 M sodium hydroxide or sodium carbonate (but not sodium hydrogen carbonate) in aqueous dioxane at room temperature to give p-toluenesulfinate anion, ethylene. and a carboxylate 215 Thus, this ester function complements the methylsul-fonylmethyl function (see section 6.4) derived from methylthiomethyl esters in its base-sensitivity. Electron withdrawing groups (e.g., p-nitro) on the aryl ring increase base lability — a feature that has been exploited for the protection of the 2f hydroxyl function in oligoribonucleotide synthesis.216... 

DOT CLASSIFICATION 8 Label Corrosive SAFETY PROFILE Poison by ingestion, inhalation, and intravenous routes. Questionable carcinogen with experimental tumorigenic data. Experimental reproductive effects. A corrosive. A skin and severe eye irritant. An allergen. Has been reported as causing irritation of mucous membranes and heart rhythm disturbances in humans. Violent reaction with water -(above 30°C), acetone + water, methanol, methanol + sodium hydrogen carbonate, 2-ethoxyethanol, dimethyl formamide, 3-butanone + sodium hydroxide + water, allyl alcohol + sodium hydroxide + water (at 28°C). When heated to decomposition it emits toxic fumes of CL and NOx. See also CHLORIDES. 

A similar reaction carried out with cyclohexene led to the formation of 3-methoxycyclohexene When this reaction sequence is carried out with internal olefins, the methoxyalkyl phenyl tellurium oxides are not stable and decompose to methoxyalkenes in the basic medium required for the hydrolysis of the methoxyalkyl phenyl tellurium dibromides(see p. 583). Aqueous solutions of sodium hydrogen carbonate cause the same transformations at a slower rate". Thus, 5-hydroxy and 5-methoxy-4-hexyl phenyl tellurium dibromide were converted to the corresponding 5-substituted 3-hexenes. 3-Hydroxy- and 3-methoxy-l-cycloheptene were similarly obtained. ... 

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