Sodium-2-ethylhexanoate

Pd(Ph3P)4, RS02Na, CH2CI2 or THF/MeOH, 70-99% yield. These conditions were shown to be superior to the use of sodium 2-ethylhexanoate. Methallyl, crotyl, and cinnamyl ethers, the Alloc group, and allylamines are all efficiently cleaved by this method. ... 

The product was dissolved in 5 of acetone and the solution was mixed with a solution of 430 g (2.59 mols) of sodium 2-ethylhexanoate in 5.4 of acetone. The combined solutions were seeded and stirred in an ice bath for 1.5 hours. The crystalline precipitate of sodium 7-(D-2-formyloxy-2-phenylacetamido)-3-(1 -methyl-1 H-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylate was filtered and washed with 5 of acetone. The crystalline salt was dried overnight in a vacuum oven at 40°C to yield 1,060 g (80%) of product, melting at 182°C to 184°C. 

Diphenylmethyl 7j3-amino-7a-methoxy-3-(1 -methyltetrazol-B-yD-thiomethyl-l -oxa-dethia-3-cephem-4-carboxylate Aluminum chloride Sodium-2-ethylhexanoate... 

To a solution of 7 (d-p-hydroxyphenyl-0i-carboxyacetamido-7(l-methoxy-3-(1-methyl-tetrazol-5-vl)thiomethyl-1-oxadethia-3-cephem4-carboxylic acid (359 mg) in methanol (7 ml) is added a solution of sodium 2-ethylhexanoate in methanol (2 mols/liter 1.73 ml) at room temperature. After stirring for 10 minutes, the reaction mixture is diluted with ethyl acetate, stirred for 5 minutes, and filtered to collect separated solid, which is washed with ethyl acetate, and dried to give disodium salt of 7 (a-p-hydroxyphenyl-a-carboxyacetamido)-7Q -methoxy-3-(1-methyl-tetrazol-5-vl)thiomethyl-1-oxadethia-3-cephem4-carboxylic acid (342 mg). Yield 885%. Colorless powder. MP decomposition from 170°C. 

C2H5NaO 141-52-6) see Azelastine Einorfazone Methyprylon Oseltamivir Pentobarbital Promestriene Propallylonal Protionamide sodium 2-ethylhexanoate... 

A number of organic compounds, such as N, N-dimethylaniline-present in amoxycillin trihydrate cephalexin cloxacillin sodium dicloxacillin sodium 2-ethylhexanoic acid-in amoxycillin sodium 4-chlorophenol-in clofibrate acetone and butanol-in daunorubacin hydrochloride cineole limonene ratio-in dementholised mint oil etc ... 

Another method for deallylation is the Pd-catalyzed transfer of the allyl group to reactive nucleophiles. Sodium 2-ethylhexanoate [141], morpholine [142], dimedone [143] and AA-dimethylbarbituric acid [144] are used as allyl scavengers. It is claimed that benzenesulfinic acid 331 or sodium toluenesulfinate are the best allyl scavengers [145]. 

The mixture was filtered, the ethyl acetate layer separated and washed with three 100 ml portions of water, dried over Na2S04, filtered and treated with 30 ml of sodium 2-ethylhexanoate in n-butanol (34 ml = 0.1 mol). The oil which settled out was scratched to induce crystallization. After stirring for 20... 

The 6,6-dibromo-l,l-dioxopenicillanic acid in presence of Fe was converted to the 1,1-dioxopenicillanic acid (sulbactam acid). The sulbactam acid was treated by sodium 2-ethylhexanoate and crude sulbactam sodium was obtained. 

Fitt, J., Prasad, K., Repic, O., Blacklock, T. J. Sodium 2-ethylhexanoate a mild acid scavenger useful in acylation of amines. Tetrahedron Lett. 1998, 39, 6991-6992. 

The product was dissolved in 5 of acetone and the solution was mixed with a solution of 430 g (2.59 mols) of sodium 2-ethylhexanoate in 5.4 of acetone. The combined solutions were seeded and stirred in an ice bath for 1.5 hours. The crystalline precipitate of sodium... 

During efforts directed towards the synthesis of carbapenem antibiotics, an efficient method for the Pd(OAc>2-catalyzed cleavage of allyl esters was developed. Sodium 2-ethylhexanoate was used as the allyl group scavenger. ... 

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