Sleep factors interleukin

Another controversial but exciting area of research is the potential role of serotonin in sleep. 5-Hydroxytryptamine may trigger slow-wave sleep (non-REM sleep), whereas the muscarinic AChR and NE are involved in REM sleep (rapid-eye-movement sleep, paradoxical sleep, dream sleep). In addition to the aminergic regulation of sleep, recent research has identified several other presumed sleep factors delta-sleep-inducing peptide, sleep-promoting substance, interleukin-1, and muramyl peptides. [Pg.254]

Recombinant tumor necrosis factor and interleukin 1 enhance slow-wave sleep. Am. J. Physiol. 253, R142-9. [Pg.335]

Kubota T, Kushikata T, Fang J, Krueger JM. Nuclear factor-kappaB inhibitor peptide inhibits spontaneous and interleukin-1 beta-induced sleep. Am J Physiol Regul Integr Comp Physiol 2000 279 R404-R413. [Pg.530]

Liu H, Kiu J, Xiong S, Sgen G, Zhang Z, Xu Y. The change in interleukin-6 and tumor necrosis factor in patients with obstructive sleep apnea syndrome. J Tongji Med Univ 2000 20 200-202. [Pg.531]

GABA opioids, interleukin-1 (IL-1), and tumor necrosis factor a (TNFa) all inhibit REM sleep. [Pg.227]

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