Sinomenium acutum

Sinomenium acutum Rehd and Wils. Sinactine (Z-tetrahydro-epiberberine) and other alkaloids (p. 268). [Pg.329]

Opium (Papaver somniferum) Benzylfsoquinolines Phthalide isoquinolines Morphine Sub-group, Sinomenium acutum Other Papaver spp. Rhoeadine, etc.. ... [Pg.809]

Sinomenium acutum (Thunb.) Rehd. et Wils. S. diversifolium Diels. Japanese Fuag Ji, Qing Teng See Cocculus diversifolius ... [Pg.151]

Cocculus diversifolius, C. thunbergii, Menispermum dauricum, Sinomenium acutum Menispermum dauricum Lycium chinense Hedyotis diffusa... [Pg.382]

Fibraurea chloroleuca (Menispermaceae) pw 113,1153 78 Heptacyclum zenkeri (Menispermaceae) phy 22,321 83 Penianthus zenkeri (Menispermaceae) phy 22,321 83 Sinomenium acutum (Menispermaceae) nm 48,287 94 Thalictrum fauriei (Ranunculaceae) jps 69,1061 80 Xylopia vieillardii (Annonaceae) jnp 54, 466 91... [Pg.109]

Antizoma angustifolia (Menispermaceae) jnp 51,584 88 Croton linearis (Euphorbiaceae) rlq 1,140 70 Sinomenium acutum (Menispermaceae) 11yd 33s, 1 70 Thalictrum foetidum (Ranunculaceae) pm 56, 337 90... [Pg.152]

Croton plumieri (Euphorbiaceae) phy 8,777 69 Croton stenophyllus (Euphorbiaceae) ref 16,45 82 Sinomenium acutum (Menispermaceae) bydx 23, 235 91 Stephania brachyandra (Menispermaceae) cty 13,1 82... [Pg.153]

Sterculiaceae) [seed], Camellia sinensis (tea) (Theaceae) [leaf] Sinomenium acutum (Menispermaceae) major metabolite of Caffeine Tabernanthe iboga (iboga),... [Pg.168]

Melia azedarach (Meliaceae) Sinomenium acutum (Menispermaceae)... [Pg.271]

Sophora falvescens (Ku shen) contains a variety of matrine alkaloids, such as aloperine, cytosine, lehman-nine, matrine, oxymartine, oxysophocarpine, sophocar-pine, sophoramine, and sophoridine, the flavonoid kushenol, and the saponin sophoraflavoside. Ku shen is a Chinese herbal remedy made from the root of S. falvescens. And Qing luo yin, a Chinese herbal remedy for rheumatoid arthritis, is a combination of extracts of Dioscorea hypoglauca, Phellodendron amurense, Sinomenium acutum, and S. flavescens. [Pg.1315]

Liriodenine was found to be the mutagenic principle in a methanol extract of the root, root stalk, and stem of Sinomenium acutum (Menispermaceae). The alkaloid exhibited potent mutagenic activity towards Salmonella typhimurium strains TA98 and TA100 in the presence of liver homogenate (S9 mix)(10.9 and 90.7 revertants/nmol, respectively), and accounted for about 40% of the mutagenicity of the total methanol extract. The mutagenic potency of liriodenine is comparable to that of benzo[a]pyrene [295]. [Pg.151]

This alkaloid, which can be obtained from the plant Sinomenium acutum, is now recognized as the optical antipode of 7-methoxythe-bainone [xxvi]. It can be converted to the antipode of dihydrothebain-one. Sinomenine and its derivatives are fully discussed in Chapter XXVI. [Pg.225]

The alkaloid sinomenine was first isolated from the stem and roots of the Japanese plant Sinomenium diversifolius by Ishiwari in 1920 [1], It also occurs in Sinomenium acutum and probably in han-fangchi [2-4], Goto [5] first called the alkaloid cucoline, but subsequently adopted the name sinomenine. [Pg.333]

Although in P. somniferum and Sinomenium acutum the biosynthesis of the morphinane bases can be carried out with (+)-reticuline as starting material, these bases and also protopine (101a) cannot be obtained biosyn-thetically in satisfactory yield from (+)-tembetarine chloride (reticuline methochloride). Similar results were obtained with D. spectabilis (683). Important intermediates of the biosynthesis between tetrahydroprotober-berine and protopine alkaloids are the compounds of the dihydroprotopine type (102), which were prepared in high yield by partial synthesis with cyanogen bromide (von Braun method) (684). The biosynthesis of pro topine alkaloids is also discussed in Section III,N. [Pg.464]

Sinomenine is the main alkaloid of the roots and stems of Sinomenium acutum Rehder and Wilson and Sinomenium diversifolius Diels, climbing plants indigenous to the woods of southern Japan (89). Sinomenine contains a hydrophenanthrene nucleus and an ethanamine bridge and is structurally very similar to morphine and codeine. The configuration at the asymmetric centers, C-5, C-9, C-12, and C-14 is the mirror image of those in morphine it affords a route to interesting enantiomorphs of morphins and morphinone derivatives. [Pg.52]

Sinomenium acutum Rehder Sinactine (161), Tuduranine (162), Acutumine... [Pg.86]

Sinoacutine C H2,N04 327.38 198 -I12°(C2H50H) Sinomenium acutum, Corydalis-, Glaucium-and Nandina species 4090-18-0... [Pg.409]

Sinomenine, a natural alkaloid from Sinomenium acutum, is reported to be a stimulant in vascular smooth muscle cell dedifferentiation and neointimia formation. This alkaloid is considered a candidate to be used in clinical treatment of vascular proliferative diseases. Present findings suggest that sinomenine also could suppress osteoclast formation and Mycobacterium tuberculosis H37Ra-induced bone loss by mediating signaling pathway of... [Pg.360]

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