Single-stranded DNA-binding proteins SSBs

Chase, J.W., Merrill, B.M., and Williams, K.P. (1983) F sex factor encodes a single-stranded DNA binding protein (SSB) with extensive sequence homology to Escherichia coli SSB. Proc. Natl. Acad. Sci. USA 80, 5480-5484. 

StabiUzation of unwound template strands Single-stranded DNA-binding protein (SSB) Single-stranded DNA-binding protein (SSB)... 

Single-stranded DNA binding proteins (SSBs) bind to this short region of ssDNA, which promotes further unwinding of a nearby A+T-rich region. 

Mismatch repair protein mutL Single-stranded DNA-binding protein ssb DNA repair uvrA Helicase dnaB RNA polymerase frpoB subunits rpoCJ... 

Glover BP, McHenry CS. The chi psi subunits of DNA polymerase III holoenzyme bind to single-stranded DNA-binding protein (SSB) and facilitate replication of an SSB-coated template. J. Biol. Chem. 1998 273 23476-23484. 

Single-stranded DNA Binding Protein (SSB) enhances the activity of the helicase and prevents the unwound DNA from renaturing (Fig 11.16). 

So far, NECEEM was used to study the interaction between several proteins and DNA such as an Escherichia coli single-stranded DNA-binding protein (SSB) and a fluorescently labeled oligonucleotide (ssDNA), Taq DNA polymerase and its aptamer, thrombin and its aptamer, Tau protein and single-stranded and double-stranded DNA, protein farnesyltransferase (PFTase) and its aptamer, MutS protein and its aptamer, h-Ras protein and its aptamer, and Mef2c protein and double-stranded DNA it naturally binds. It has also been used to study protein-peptide interactions. ... 

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