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Signalling mechanisms pharmacodynamics

Drug-receptor interactions Dose-response relationships Molecular models of receptors and signal transduction mechanisms Biotransformation Pharmacokinetics Pharmacodynamics... [Pg.19]

The pharmacodynamics phase corresponds to the way in which a drug binds to receptors, transporters, and channels in order to elicit a particular action from a cell (this is called signal transduction). This is referred to as the mechanism of action. While researchers attempt to determine the mechanism of action of promising compounds in order to better predict therapeutic outcomes and unexpected effects, often times the exact mechanism remains unknown, even after the drug has been approved for use. [Pg.76]


See other pages where Signalling mechanisms pharmacodynamics is mentioned: [Pg.46]    [Pg.16]    [Pg.12]    [Pg.115]    [Pg.717]    [Pg.492]    [Pg.152]    [Pg.333]    [Pg.512]    [Pg.75]    [Pg.288]    [Pg.342]    [Pg.550]    [Pg.305]   
See also in sourсe #XX -- [ Pg.165 ]




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