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Sialic acid in glycoproteins

Corfleld AP, Schauer R (1982) Metabolism of sialic acids. In Schauer R (ed) Sialic acids - Chemistry, metabolism and function. Springer, Wien, pp 195-261 Corfleld AP, Higa H, Paulson JC, Schauer R (1983) The specificity of viral and bacterial sial-idases for alpha(2-3)- and alpha(2-6)-linked sialic acids in glycoproteins. Biochim Biophys Acta 744 121-126... [Pg.147]

The special importance of sialic acids in glycoproteins may lie in the negative electrical charges and the resultant Ca2+-binding properties that they impart to... [Pg.185]

D5. Dische, Z., Fucose and sialic acid in glycoproteins of the mucus of the digestive tract. Federation Proc. 19, 904-910 (1960). [Pg.345]

Anumula, K. R. Rapid quantitative determination of sialic acids in glycoproteins by high-performance liquid chromatography with a sensitive fluorescence detection. Anal. Biochem. 230 24-30,1995. [Pg.354]

R. Schauer and J.P. Kamerling, Chemistry, biochemistry and biology of sialic acids, in Glycoproteins IT (J. Montreuil, J.F.G. Vliegenthart and H. Schachter, editors), 1997, Elsevier Science B.V., Amsterdam, pp 243-402. [Pg.1619]

Dimitrov, G. D., 1973, Spectrophotometric method for qualitative and quantitative determination of sialic acid in glycoproteins and glycopeptides, Hoppe-Seyl. Z. 354 121. [Pg.51]

Almost total release of sialic acids from glycoproteins or oligosaccharides can be achieved108,107 by heating the material in 0.05 M sul-... [Pg.147]

Sialic acid seems to be involved not only in regulation of the lifetime of soluble, serum glycoproteins but also of mammalian blood-cells. It was observed by Woodruff and Gesner474 that desialylated lymphocytes are reversibly trapped in liver they recirculate to the blood stream after about 24 h. This phenomenon was confinned with Listeria-specific, mouse T lymphocytes, which accumulated in the liver for one day, in contrast to the control cells.60 Reappearance of these cells in the circulation after one day may be explained by re-sialylation of their membrane glycoconjugates. This time period is in the range observed for the turnover of sialic acid in cell membranes, lasting, for example, for 33 h in rat-liver hepatocytes.475... [Pg.221]

Fetuin is a glycoprotein which has titratable groups associated with its carbohydrate moiety (sialic acid) in addition to those present on the protein. Spiro (1960) has determined the titration curve of the native protein, as well as that of a preparation from which sialic acid had been removed. The group count differed only in the number of groups assignable to sialic acid. In particular, the value of S was the same for both proteins. It is clear from these results that the combination of sialic acid with the protein does not involve any of the basic groups of the protein. [Pg.138]

Morell AG, Gregoriadis G, Scheinberg HI, Hickman J, Ashwell G. The role of sialic acid in determining the survival of glycoproteins in the circulation. J Biol Chem 1971 246 1461-7. [Pg.499]

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See also in sourсe #XX -- [ Pg.109 , Pg.516 ]

See also in sourсe #XX -- [ Pg.2 , Pg.4 , Pg.10 , Pg.11 , Pg.71 ]



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