Sialic acid abbreviations

The sialic acid abbreviations used in the text are listed in Table I. They are drawn up on the basis of a Round Table discussion at the Fifth International Symposium on Glycoconjugates which took place at Kiel in 1979. 

Acylated neuraminic acids and other derivatives of neuraminic acid may also be called sialic acids (abbreviated Sia) when the nature of the (V-acyl substituent(s) is not relevant or is unknown. ... 

Names, Abbreviations, and Indication of Nature and Position of the N- and O-Substituents of Natural Sialic Acids"... 

Vitamin C (ascorbic acid, Box 18-D) is another important sugar derivative. Neuraminic acid is a 9-carbon sugar made by transferring a 3-carbon piece onto a hexosamine. Its N-acetyl and N-glycolyl derivatives are called sialic acids. Their names may be abbreviated NeuAc and NeuGl, respectively, or simply as Sia (see also Fig. 4-4). 

Fig. 10.4 Structures of the Lewis and blood group antigens expressed in H. pylori strains. See Moran (2008) for details. Abbreviations Fuc, fucose Gal, galactose GalNAc, IV-acetyl-galactosamine GlcNAc, A-acetyl-glucosamine Neu5Ac, A-acetyl-neuraminic (sialic) acid...

Figure 2 Mammalian monosaccharides and nucleotide sugars. (A) Chemical structures, common names, and abbreviations of the 11 monosaccharides found in mammalian glycans as well as ManNAc, the precursor for sialic acids. (B) Examples of the three classes of nucleotide sugars are provided by UDP-GIcNAc (Glc, GIcA, Gal, GalNAc, and Xyl also use UDP), GDP-Man (Fuc also is linked to GDP), and CMP-Neu5Ac/Gc (IdoA is produced by postsynthetic epimerization of GIcA and therefore does not require a nucleotide sugar).

Scheme L Synthesis of a2,64inked sialyl-N-acetyllactosamine using a one-pot multi-enzyme system with in situ regeneration of CMP-Neu5Ac. Abbreviations for enzymes CSS, CMP-sialic acid synthetase NMK, nucleoside monophosphate kinase PK, pyruvate kinase PPase, pyrophosphatase. Abbreviations for compounds PEP, phosphoenolpyruvate ADP, adenosine 5 -diphosphate ATP, adenosine 5 -triphosphate CMP, cytidine 5-monophosphate CDP, cytidine 5 -diphosphate CTP, cytidine 5-triphosphate LacNAc, N-acetyllactosamine NeuSAc, N-acetylneuraminic acid PPi, inorganic pyrophosphate.

Figure 28-3. The schematic structure of ganglioside G i. The nomenclature is as follows G stands for ganglioside the subscript letter indicates the number of sialic acid residues the numeral is equal to 5 - (number of neutral sugars). Abbreviations GalNAc = A-acetylgalactosamine, Gal = galactose Glc = glucose NANA = A-acetylneuraminic acid (sialic acid).

Abbreviations used for sialic acids (Sia) are included GlcA D-glucuionic acid... 

For the abbreviation of natural and synthetic sialic acids see Tables 1 and 13, respectively. 

Fig. 20.1. Abbreviated scheme of the synthesis of a diantennary N-glycan. Fucose modification has been omitted. 20.1, Phosphomannomutase 2 (PMM2) 20.2, phosphoman-nose isomerase (PMI) 20.3, glucosyltransferase I (GT I) 20.4, mannosyltransferase VI (MT VI) 20.5, dolichol phosphate-mannose synthase-1 (DPM synthase-1) 20.5, N-acet-ylglucosaminyltransferase II (GnT II) 20.7, glucosidase I (G I) GDP, guanosine diphosphate Marly mannose GlcNACy N-acetylglucosamine Do/, dolichol P, phosphate G/c, glucose Gal galactose SiUy sialic acid. Dotted arrow indicates multiple steps...

Table 1. Colorimetric analysis of the sialic acids. Molar absorption coefficients The molar absorption coefficients are noted for the different sialic acids using the commonly used colorimetric assays. The chromophore was measured at the absorption maximum, noted at the head of each column. Abbreviations of the sialic acids are those used in chapter B, Table 1... 

Abbreviations of the sialic acids are those used in chapter B, Table 1.—Not determined. 

Example of the one-pot, three-enzyme synthesis of Siaa2-6GalbpNP (32) and Siaa2-3GalppNP (33). Abbreviations Pm NeuA aldolase from, Pasteurella multocida NmCSS CMP-synthetase CMP-sialic acid synthetase from Neisseria meningitidis PmSTI P. multocida sialyltransferase Pd2,6ST a2-6-sialyltransferase from Photobacterium damsela GaippNP p-nitrophenyl p-galactoside. 

Figure 3. Structure of the monosialoganglioside, Guif galactosyl-N-acetyl-galactosaminyl-(sialyl)-galactosylglu-cosylceramide. The abbreviations used are Cer, ceramide Glc, glucose Gal, galactose GalNAc, N-acetylgalactosamine NAN, N-acetylneuraminic acid (sialic acid).

Naturally Occurring Sialic Acids and Suggested Abbreviations"... 

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