Short chain chlorinated paraffins toxicity

Wang Y, Fu J, Jiang G (2009) The research of environmental pollutions and toxic effect of short chain chlorinated paraffins. Environ Chem 28 1-9 (in Chinese)... 

Muir DCG, Bennie D, Teixeira C, Fisk AT, Tomy GT, Stem GA, Whittle M (2001) Short chain chlorinated paraffins are they persistent and bioaccumulative In Lipnick R, Jansson B, Mackay D, Patreas M (eds) Persistent, bioaccumulative and toxic substances, vol 2. ACS Books, Washington, DC, pp 184—202... 

In Japan, no regulation for short-chain chlorinated paraffins (SCCPs) had been implemented and SCCPs are not included in the list of designated chemical substances for the Pollutant Release and Transfer Register (PRTR). Risk assessment of SCCPs, which was performed in Europe, the U.S, Canada, and Australia, was not conducted in Japan, and the releases of SCCPs into the environment, which can be obtained from the Toxics Release Inventory (TRl) in the U.S., are not available. 

The acute toxicity of chlorinated paraffins to mammals, binds, and fish is very low (8), but over longer periods of exposure certain chlorinated paraffins have proved to be toxic to some aquatic species. However, the very low water solubility of chlorinated paraffins has made studies on aquatic species complicated. Laboratory experiments in which the chlorinated paraffins had been artificially solubilized showed only the short-chain grades to be toxic at low concentration other longer-chain grades showed no adverse effects on the majority of aquatic species tested. The degree of solubilization achieved in the laboratory is unlikely ever to be experienced in the environment and is of doubtful environmental relevance (9). 

CSTEE (1998) Scientific committee on toxicity, ecotoxicity and the environment opinion on the risk assessment of short chain length chlorinated paraffins. Available at http //ec.europa. eu/health/ph risk/committees/sct/docshtml/sct out23 en.htm... 

IRDC (International Research and Development Corporation) (1981) 14-Day oral toxicity study in rats with chlorinated paraffin 58% chlorination of short chain length n-paraffin. Studies conducted for the Working Party of the Chlorinated Paraffin Manufacturers Toxicology Testing Consortium (Report No 438-006)... 

EG G Bionomics (1983) The acute and chronic toxicity of a chlorinated paraffin (58% chlorination of short chain length n-paraffins) to midges (Chironomus tentans). EG G Bionomics, Wareham, MA, pp 39 (Report No BW 83-6-1426)... 

Madeley JR, Maddock BG (1983b) Toxicity of a chlorinated paraffin over 60 days, (iv) Chlorinated paraffin - 58% chlorination of short chain length n-paraffins, ICI Confidential Report BL/B/2203 (cited from EU 1999)... 

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