Sesquiterpene pyridine-type alkaloid

Products isolated from plants of the Celastraceae family have showed insecticidal and antifeedant activities, as discussed earlier. The compounds reported belong to the agarofuran sesquiterpene-type and sesquiterpene pyridine-type alkaloids. Nevertheless, the only description of insecticidal activity of quinone methides found is from Avilla et al [102], Despite the fact that the compounds assayed were known the... 

Celastraceae also elaborate other, more complex, alkaloids, also polyester sesquiterpenes, incorporating a macrocycle derived from an evonic, wilfordic, cassinic or other type pyridine dicarboxylic acid with an additional alkyl chain of the basic eudesmane cycle at C-3 and C-7 (Table III). Celastraceae alkaloids are well-documented for the European and Asian genera, particularly Catha, Celastrus, Euonymus and Trypterigium but are relatively rare among the Latin... 

Alkaloids that possess an aromatic pyridine ring often are called pyridine alkaloids (Leete, 1980 Pinder, 1993 Strunz and Findlay, 1985) approximately 250 alkaloids of this type are known (Verpoorte et al., 1991). Although many are derived from nicotinic acid (Fig. 28.18), others arise from aro-matization of piperidine alkaloids and other pathways (Waller and Nowacki, 1978). This chapter includes several of the most important compounds of this type, although others (such as a number of monoterpene-derived alkaloids, Nu-phar alkaloids, and sesquiterpene alkaloids of the Celastra-ceae) are discussed in Chapter 36. 

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