Macrocyclic derivative

A different approach to the preparation of boron macrocycles can be made by using diboronates 69-71 for the construction of the macrocyclic derivatives... 

Fig. 19. Transformation of diboronates 69-71 to macrocyclic derivatives was not possible, however, with 4,4 -biphenyldiboronic acid 72 compound 73 is formed...

There are good reasons for nature choosing macrocyclic derivatives for the important complexes just mentioned - enhanced kinetic and thermodynamic stabilities are bestowed on the respective complexes by the... 

The sulfimide group R2S = NR is isoelectronic with R2S = O, and recent studies have revealed the first examples of macrocyclic derivatives from reaction of the thia crown with MSFI.155,156 These compounds are of interest as ligands in their own right, and also because they provide a means of functionalizing the thiacrown at the S atom and hence the possibility of introducing pendant groups. 

Rowan, S. J. Sanders, J. K. M. Macrocycles derived from cinchona alkaloids A thermodynamic vs. kinetic study. J. Org. Chem. 1998, 63, 1536-1546. 

Polyaza macrocycle derivatives have been employed in a number of analytical applications." " For example, polymer-immobilized cyclam has been employed for the preconcentration of manganese in seawater prior to analysis." ... 

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