Serum collection device

Collection of specimens for serum Al analysis can be a complicating factor. Most of the common evacuated blood collection devices used in phlebotomy today have rubber stoppers that are made of Al silicate. Puncture of the rubber stopper for blood collection is sufficient to contaminate the sample with Al to produce an abnormal concentration of Al. Typically, blood collected in standard evacuated blood tubes... 

In a follow-up study, the same authors examined the applicability of the same device for relevant protein samples and investigated the main contributions to band broadening [82]. As a consequence of the small depth of the beds, zone spreading caused by Joule heating was shown to be negligible (see Sect. 3.1.1). Cross fields of up to 100 V/cm were applied for the separation of human serum albumin, ribonuclease A and bradykinin. The feasibility of fraction collection was demonstrated with four collected fractions of a whole rat plasma sample. Off-line analysis of these four isolated fractions by CE indicated the separation of serum albumins and globulins. 

In direct headspace analysis, the sample e g. serum or urine, is equilibrated with the headspace in a suitable container. A protion of headspace gas is then injected for analysis. More elaborate headspace trapping devices combine separation of the volatiles from the sample matrix with subsequent enrichment of the constituents. Such a system, suitable for small volumes of body fluids, is known as the transevaporator sampling technique. It contains a microcolumn packed with Porasil E (pore silica gel), into which the sample is injected. In one mode of use, helium is passed through the column to remove the volatiles which are then collected in a trap (Tenax-GC, a porous polymer, 2,6-diphenyl-p-phenylene oxide). 

The KIS test is marketed for use at either abattoirs or laboratories for the analysis of kidney samples to identify animal carcasses with non-compliant concentrations of antimicrobial residues present in the edible tissues. The KIS reagents are supplied as self-contained and pre-measured for a single use presented in a disposable swab format. The swab is directly inserted into an incision made in the kidney test sample to collect a sample of the serum for analysis via microbial inhibition. The impregnated swap is then inserted into a device containing a tube diffusion MIA... 

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