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Serotonergic hallucinogens effects

Mechanisms of Action of LSD-Like Drugs Pharmacokinetics of LSD-Like Drugs Psychotherapeutic Uses Effects of Serotonergic Hallucinogens Adverse Effects of Serotonergic Hallucinogens... [Pg.290]

Less information is available about the other serotonergic hallucinogens, but most are similar. One noteworthy exception is dimethyltryptamine (DMT), which is usually taken by using the bark of the Virola as a snuff or by smoking it. Its effects begin within minutes of use but persist for only about 60 minutes (Dal Cason Franzosa, 2003). [Pg.299]

Serotonergic hallucinogens A class of drugs that includes LSD and drugs with similar effects and mechanisms of action (Chapter 12). [Pg.448]

Heym, J. Rasmussen, K. and Jacobs, B.L. Some behavioral effects of hallucinogens are mediated by a postsynaptic serotonergic action ... [Pg.299]

Further evidence for serotonergic mediation of the effects of hallucinogens was provided by a report on the development of functional supersensitivity in the rat with a chronic denervation of spinal 5-HT neurons. Nygren et al. (138) reported that rats pretreated with intracistemally administered 5,6-dihydroxy-tryptamine (5,6-DHT), a 5-HT neurotoxin, subsequently showed greater hindlimb extensor facilitations to 5-MeODMT or L-tryptophan + nialamide at 1 week versus 1 day following pretreatment. [Pg.26]

Sloviter, R. S., Drust, E. G., Dammiano, B. P., and Conner, J. D. (1981) A common mechanism for lysergic acid, indolealkylamine and phenethylamine hallucinogens Serotonergic mediation of behavioral effects in rats. J. Pharmacol. Exp. Ther., 214 231-238. [Pg.54]


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