Sermorelin acetate

Sermorelin acetate is the acetate salt of an amidated synthetic 29-amino acid peptide (GRF 1 -29 NH2) consisting of 44 amino acid residues. The free base of sermorelin has the empirical formula C 149 H 246 N 44 O 42 S and a MW of 3358 Da. 

USA sermorelin acetate peptide Geref Recombinant 1-29 residues of human growth hormone-releasing hormone Hormone... 

In addition to GH, sermorelin acetate (geref), a synthetic form of human GHRH containing residues 1-29, is FDA-approved for diagnostic purposes. Sermorelin used therapeutically (30 /tg/kg/day given subcutaneously) was less effective than GH in clinical trials. This agent will not work in patients whose GH deficiency results from defects in the anterior pituitary. 

Each vial contains 0.5 mg of sermorelin (as the acetate) and 5 mg of mannitol. The pH is adjusted with dibasic sodium phosphate and monobasic sodium phosphate buffer. Each 1.0-mL vial contains 1.0 mg of sermorelin (as the acetate) and 5 mg of mannitol. The pH is adjusted with dibasic sodium phosphate and monobasic sodium phosphate buffer. 

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