Separation ionization

Separate ionization constants designated Ki and K2 respectively characterize the two successive ionization steps of a dicarboxylic acid... 

FIG. 19-60 Internal configuration of roll-tvpe electro.static. separator, ionizing Diode. (Cowiosij Carpco, Inc.)... 

Acidic modifier Trifluoroacetic acid Formic acid Propionic acid Acetic acid Ionization completely suppressed Good separation/ionization Good separation/ionization Best separation/ionization... 

Owing to the rising cost of solvent disposal, CE is becoming a more attractive method for extract analysis. The method makes it easy to separate ionizable substances using minimal amounts of solvents. On-column detection removes the coupling problems, and the separation power is comparable to that obtained in capillary gas chromatography. If alkaloids have to be analyzed, this method is currently the most suitable. 

A pipe channel, or mold, with several inlets or outlets. An instrument capable of separating ionized molecules of different mass/charge ratios and measuring the respective ion currents. 

Sample Preparation Separation Ionization Mass Aralyzer(s) Detection Library Scanning/ Identification... 

To implement an experimental design in chemical ecology, suitable for metabolomic analyses, the two major analytical methods currently used are mass spectrometry (MS) and nuclear magnetic resonance (NMR), the choice of which first depends on the conditions of metabolite extraction and will then depend on the conditions used for separation ionization, and also on the solubility of the chemical constituents. The bases and principles of these widely used methods in chemical ecology are presented in Chapter 8. The technological progress in this domain is considerable [ZHA 12]. 

Ion traps with an external source appeared on the analytical chemistry market a few years after their internal ionization homologues. This type of device separates ionization and detection, as in the case of a quadrupole. The ions are extracted from the source, accelerated, and focalized by an extraction system analogous to those desaibed for quadrupoles. An ion gate permits the sequential introduction of ions into the trap. 

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