Senecio alpinus

To date, about 25 taraxastanes have been isolated, predominantly from Asteraeeae Representatives inelude (+)-20-Taraxasten-3p-ol (v /-taraxasterol) and (+)-20(30)-taraxasten-3p,16p-diol (amidenediol) from lion s tooth Taraxacum officinale and Arnica montana as well as 20-taraxasten-3p,16p-diol (faradiol) from Arnica mon-tana, Tussilago farfara, Senecio alpinus and gold-bloom Calendula officinalis (all Asteraeeae). 

KlAsek, a., T. Reichstein, and F. Santavy Die Pyrrolizidin-Alkaloide aus Senecio alpinus (L.) Scop., S. subalpinus Koch und S. incanus L. subsp. carniolicus (Willd.) Br.-Bl. Helv. Chim. Acta 51, 1088 (1968). 

Pterophorine and inaequidenine, two other dihydropyrrolizinone alkaloids, were previously isolated from Senecio inaequidens DC. (cf. Vol. 8, pp. 54-56). Senecionine and retrorsine have now also been shown to be present in this species.31,32 7-Angelylheliotridine (43) has been isolated from S. ovirensis ssp. gaudinii.32,33 The cause of poisoning in dairy cattle in Switzerland was found to be S. alpinus.34 Nine known pyrrolizidine alkaloids were isolated from this species, and the major constituent was seneciphylline. Otosenine, floridanine, and doronine are present in 5. othonnae.35 The extraction of seneciphylline and platyphylline from S. platyphylloides has been studied by a variety of methods.36... 

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