Semilogarithmic graph

The general function giving linear plots on semilogarithmic graphs is ... 

It is a worthwhile exercise first to construct a preliminary inhibitor plot. Holding the substrate concentration constant at a value around the Km value, effects of a range of concentrations of inhibitor are assessed and plotted on a semilogarithmic graph, in the same way that a preliminary estimate for Km was... 

When Eq. (12-31) is plotted on semilogarithmic graph paper, a straight line is obtained for values of (W - W,)/ Wc - W,) < 0.6. It is in the straight-line portion that the approximate form [Eq. (12-33)] applies. 

Please note Although it might seem easier to calculate a and directly from the graph as slopes, this is complicated by the fact that this semilogarithmic graph paper uses a logic scale rather than a natural log scale on the y-axis. A simple way to circumvent this difficulty is to calculate the values of a and from their respective half-lives. 

Fig. 1.11 Semilogarithmic graph showing the decline in plasma drug concentrations (with time) following the intravenous injection of a single dose (10mg/kg). The biexponential equation of the disposition curve is shown (inset). The half-life, U /2 (p), of drug is calculated from the expression U /2 (p) = 0.693/(3, where (S (0.0058 min-1) is the negative logarithm of the slope of the linear terminal portion (elimination phase) of the disposition curve. (Reproduced with permission from Baggot, (1977).)...

Fig. 2.2 Semilogarithmic graph of plasma drug concentration (o) after oral administration of a dose. The absorption phase is obtained by the method of residuals following back-extrapolation of the linear terminal (disposition) phase. Residual values are denoted by the dashed line. The zero-time intercept (in units of concentration) is log [FDosekaIV6 (ka-kd)]. (Reproduced with permission from Gibaldi Perrier (1982).)...

Figure 1.4. Plot of activity At against time on a semilogarithmic graph indicating a straight line. The slope of the line is the decay constant A of the radionuclide. The half-life h/2 is calculated from A using Eq. (1.8). Alternatively, the half-life is determined by reading an initial activity and half its value and their corresponding times. The difference in time between the two readings is the half-hfe.

Figure 1.5. The transient equilibrium is illustrated in the plot of activity vs. time on a semilogarithmic graph. The daughter activity increases initially with time, reaches a maximum, then transient equilibrium, and finally appears to follow the half-life of the parent. Note that the daughter activity is higher than the parent activity in equilibrium.

Fig. 3. BSP disappearance curves after single injection (5 mg/kg) to a normal subject. Concentrations are expressed as milligrams per 100 ml of plasma. (A) Semilogarithmic graph. (B) Linear graph of the results of Winkler (W24).

Beside bioburden, the other determinant of sterility assurance is the survival curve and its shape and its slope. It is not correct to assume that all survival curves are of the simple linear type when data is plotted on semilogarithmic graph paper. Three general types of survival curve have been reported, the exponential curve, the shouldered" curve, and the "tailed" curve (Fig. 4). 

We plotted plasma concentration versus time data on a two-cycle semilogarithmic graph paper and then determined the following ... 

This question involves two different doses of an identical drug (promethazine) in an identical dosage form (tablet), via an identical route of administration (oral) of an identical formulation (made by the same manufacturer). Plasma concentration versus time data were plotted on suitable semilogarithmic graph paper. As mentioned above, greater variation can occur in the values in parts a-d because of the technique employed. This variation, in turn, will be reflected in the answers for the peak time, peak plasma concentration and the intercept of the plasma concentration versus time profile. 

The absorption spectrum is determined from 400 - 700 nm using a suitable spectrophotometer with quartz cells. The colour formation is complete by the time the solution is brought to the mark and is stable for at least 2 h. Ethyl alcohol is used in the reference cell unless the alcohol extract is strongly coloured. In this case, the reference solvent is taken to be a 10 cm aliquot of the ethyl alcohol extract diluted to 100 cm with ethyl alcohol. The absorbance readings are plotted on semilogarithmic graph paper. The... 

The semilogarithmic graph of Fig. 2 compares the so-called floor spectra for the three SDoF oscillators with the selected natural periods T,. Each floor spectrum is obtained by using the absolute acceleration of the ith (primary) oscillator, = u(t) + Mg(0, as seismic input for a... 

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