Strychni semen

NUX VOMICA Strychni semen The drug is the seed of Strychnos nux-vomica L., family Lo minceae a tree from South-East Asia (India, Sri Lanka) where it is cultivated. (Fig. 9) ... 

Harmalae semen Powdered drug (Ig) is extracted with 10 ml methanol for 30 min under reflux, The filtrate is diluted 1 10 with methanol and 20 d i.s used for TLC. Strychni semen Powdered seeds (1 g) are defatted with 20 m n-hexane for 30min under reflux. The defatted seeds are then extracted with 10ml methanol for lOmin under reflux. A total of 30pl of the filtrate is used for TLC. 

Drug sample 1 Strychni semen (alkaloid extraction method A, 30 (il)... 

Pig. 7A Strychni (1) and Ignatii (2) semen are characterized in UV-254nra by their strong quenching zones of the two major indole alkaloids strychnine (Tl) and brucine (T2). 

Strychnos nux-vomica (Loganiaceae) is a tree that grows wild in India, Sri Lanka, and the northern area of Australia. The seeds of this plant are known as Machin-shi (in Japanese) or vomica (Strychni Semen), and they are used for maintaining health of the stomach at a medicinal dose. The seeds are also the source of strychnine nitrate, and have found use for heart and lung diseases and for Raynaud s disease. 

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