Butyl-4,6-dinitrophenol, 2-sec

Figure 10.14 Log octanol-water distribution ratios (log D,ow, broken lines) and log L-a-dioleylphos-phatidylcholine liposome-water distribution ratios (log Dflipsw, solid lines) of pentachlorophenol (PCP) and 2-sec-butyl-4,6-dinitrophenol (dinoseb) as a function of pH at 25°C and 100 mM ionic strength. Data from Escher et al. (2000).

Chemicals Used. Chemicals used in this study were technical grade products or better, dissolved in xylene with 5% emulsifying agent. The chemicals used included an oil soluble red dye, Dino-seb (2-sec-butyl-4,6 dinitrophenol), pentachlorophenol (PCP), Isopropyl N-(3-chlorophenyl) carbamate (CIPC or Chlorpropham), Iso-octyl 2,4,5- trichlorophenoxy acetate (2,4,5-T), chlorpyrifos (0, 0-diethyl 0-(3,4,6-trichloro 2-pyridyl) - phosphorothioate), and Ronnel (0-dimethyl 0-2, 4,5-trichlorophenyl) phosphorothioate) for application as a spray. The emulsifiable concentrate was diluted in water comparable to 50 gallons of spray to contain the following amounts respectively 2 lbs. for chloropryifos 4 lbs. for 2,4,5-T 3 lbs. CIPC and 2 lbs. for PCP. 

Hall, L. L., H. L. Fisher, M. R., Sumler, M. F. Hughes, and P. V. Shah. 1992. Age-related percutaneous penetration of 2-sec-butyl-4,6-dinitrophenol (dinoseb) in rats. Fundam. Appl. Toxicol. 19 258-267. 

Synonyms cas ss-ss- 2-sec-butyl-4,6-dinitrophenol 2,4-dinitro-6-sec-butylfhenol Dioxin... 

Dinitrophenol (2,4-DNP) is an uncoupler of electron transport [22,58,59] and its structural analogues, 4,6-dinitro-2-methylphenol, 2-sec-butyl-4,6-dinitrophenol and Dinoseb are important pesticides [60]. Dinoseb, which is also the major degradation product of the herbicide, Acrex by soil microorganisms [61], is responsible for health and environmental hazards [62]. 

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