Scifinder Subject

Since Pasteur separated crystalline sodium ammonium tartrate manually in 1848, many researchers have worked on the subject of enantiomeric separation. In 1939 Henderson and Rule fully separated derivatives of camphor by column chromatography using lactose as a stationary phase material [1]. Gil-Av et al. [2] were able to separate amino acid derivatives on a polysiloxane-based stationary phase by gas chromatography (GC) in 1966. Since then many approaches for a successful distinction between enantiomers have been developed for capillary GC and liquid chromatography [3]. It is still a current topic for researchers searching for chiral separation with SciFinder [4] results in 812 hits and searching for chiral recognition leads to 285 hits for the year 2003 only. 

CAS (http //www.cas.org/) is a subscription-based service with over 100 million organic, inorganic, protein, and nucleic acid structures. It can be accessed through SciFinder, which allows searches via a structural drawing program as well as searches by subject, author, or structure name. 

Subject CA Groupings CASurveyor Selects Plus Updates Titles Databases SciFinder Easy... 

Other features. The SciFinder Analyze function is a versatile capability that allows users to rank, by frequency or alphabetically, a set of references. For example, the ranking can be according to author, CA section title, journal name, publication year, CA index terms. Registry Numbers, etc. Its major function is to help users narrow the search results. Figure 34 illustrates an Analyze histogram of CA General Subject index terms relative to a search for anticonvulsants and epilepsy . 

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