Scalarane

Gavagnin M, Mollo E, Docimo T, Guo YW, Cimino G, Scalarane metabolites of the nudibranch Glossodoris rufomarginata and its dietary sponge from the South China S>e2., Journal of Natural Product 67. 2 QA—2 Q7, 2004. 

Sesterterp. scalarane. hano- and bishomoscalarane (Dictyoca"., Porif, and assoc. Nudibr., Moll. Hanson 1996) degraded C,i (fiiranic fr n Dictyocer., Pcrif, and assoc. Nudibr. Hanson 1996) praivllabdane (Halichon., Porif Hanson 1996). 

These types of compounds also showed other interesting properties, such as antineoplasic and cytotoxic activity reported from scalarane-type sesterterpenes of the Indian Ocean sponge Hyrtios erecta [109,110], and antituberculosis properties [111]. 

Hainan Is., China) contained 12o -0-acetylhyrtiolide (197) [103]. A new scalarane-type pentacyclic sesterterpene, sesterstatin 6 (198), was isolated from the Republic of Maldives marine sponge Hyrtios erecta. The structure was elucidated by analyses with HRMS and high-field 2-D NMR spec-... 

Wihiams, D.E., et al. (2009). Scalarane-based sesterterpenoid RCE-protease inhibitors isolated from the Indonesian marine sponge Carteriospongia foliascens. J Nat Prod 72 1106-1109. 

Scalarane sesterterpenoids also include alkylated derivatives, called homoscalaranes with methylations at C-20 or C-24 and... 

Four 24-homoscalaranes (213-216) that exhibited 30-95% inhibition of the growth of KB cells at 10 pg/ml were isolated from the Indonesian Phyllospongia sp. [190], From the Pacific nudibranch Glossodoris sedna were isolated several scalarane and homoscalarane compounds, but only... 

Acetoxy-3-hydroperoxy-4,11(13)-eudesmadien-12,8-olide, in D-30174 12a-Acetoxy-16)5-hydroxy-20,24-dimethyl-24-oxo-25-scalaranal, in D-10136... 

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