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Sarcoplasmic reticulum disruption

Incubation of rat aortic rings with palytoxin led to microvesiculation of the endothelial cell cytoplasm [87], Dilatation of the sarcoplasmic reticulum, densification of mitochondrial cristae (possibly reflecting calcium uptake by the tissue), and disruption of myofibrils were observed in isolated rat muscle [88], Addition of palytoxin to the perfusion medium of the perfused heart caused cardiac arrest within minutes [13], and the spontaneous beating of isolated rat auricles was rapidly inhibited [9],... [Pg.698]

Another possible mechanism of action would be that the toxins were internalised and then released into the cytosol where they could disrupt the function of subcellular components such as mitochondria and sarcoplasmic reticulum (Harris, 1984). [Pg.323]

See other pages where Sarcoplasmic reticulum disruption is mentioned: [Pg.89]    [Pg.244]    [Pg.497]    [Pg.18]    [Pg.538]    [Pg.517]    [Pg.1626]    [Pg.235]    [Pg.399]    [Pg.13]    [Pg.78]    [Pg.80]    [Pg.211]    [Pg.585]    [Pg.312]    [Pg.289]    [Pg.365]   
See also in sourсe #XX -- [ Pg.517 ]



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