Sarcoidosis pathology

Definitive diagnosis of sarcoidosis requires both a consistent clinical or radiologic appearance and biopsy-proven granulomata without bacterial or fimgal involvement. The classic pathologic finding in sarcoidosis is the epithelioid granuloma. An abnormal chest film is... 

Murata K, Itoh H et al. (1986) Centrilobular lesions of the lung demonstration by high-resolution CT and pathologic correlation. Radiology 161 641-645 Murdoch J, Muller NL (1992) Pulmonary sarcoidosis changes on follow-up CT examination. AJR Am J Roentgenol 159 473-477... 

Lenique F, Brauner MW, Grenier P, et al. CT assessment of bronchi in sarcoidosis endoscopic and pathologic correlations. Radiology 1995 194(2) 419-423. 

Figure 10 See color insert.) Pathology of pulmonary sarcoidosis. (A, B) Gross appearance of lungs. (A) Primarily dense fibrosis. (B) Primarily honeycomb change in upper lobe. (C) Typical non-necrotizing granulomas in bronchial wall. (D) Pearls on a string arrangement of parenchymal granulomas (C, D, H E stain, x40).

Rosen Y. Pathology of sarcoidosis. Semin Respir Crit Care Med 2007 28(1) 36-52. 

Padia SA, Budev M, Farver CF, et al. Intravascular sarcoidosis presenting as pulmonary vein occlusion CT and pathologic findings. J Thorac Imaging 2007 22(3) 268-270. 

Table 3 Major Pathologic Differential Diagnosis of Sarcoidosis at Biopsy and Surgical Pathology... 

Maddrey WC, Johns CJ, Boitnott JK, et al. Sarcoidosis and chronic hepatic disease a clinical and pathologic study of 20 patients. Medicine 1970 49 375-395. 

Torralba KD, Quismorio FR Jr. Sarcoid arthritis a review of clinical features, pathology, and therapy. Sarcoidosis Vase Diffuse Lung Dis 2003 20 95-103. 

Sokoloff L, Bunim JJ. Chnical and pathological studies of joint involvement in sarcoidosis. N Engl J Med 1959 260 841-847... 

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