Sample Subchronic Toxicity Tests and Commonly Used Species

21-Day Dermal Toxicity 90-Day Dermal Toxicity Inhalation Toxicity Neurotoxicity  

Commonly Used Species Mouse, rat, and/or dog Rat or rabbit Rat or rabbit Rat 

Many drugs are prescribed for short-term use consistent with the time periods of exposure used in subchronic tests. Therefore, to reproduce the expected pattern of use by consumers, subchronic studies are often used in drug testing. Subchronic tests are also required for food additives, and results must indicate that the chemical is safe for its intended use in order to be registered for use. 

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Table 5.3. Sample Subchronic Toxicity Tests and Commonly Used Species...

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