Salerno

Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Salerno, Via Ponte Don Melillo, 86 Fisciano, Italy... 

Gabriele B, Salerno G, Costa M, Chiusoli GP (1995) J Organomet Chem 503 21... 

Chiusoli GP, Costa M, Masarati E, Salerno G (1983) J Organomet Chem 255 C35... 

PANNO M L, SALERNO M, PEZZI V, SISCI D, MAGGIOLINI M, MAURO L, MORRONE E G, ANDO S (1996) Effect of oestradiol and insulin on the proliferation pattern of oestrogen and progesterone receptor contents in MCF-7 cells. J Cancer Res Clin Oncol. 122 745-9. 

I Chem. and Food Engineering Dept., Salerno University... 

Dipartimento di Chimica, Universita di Salerno, Via ponte don MelUlo, 84084 Fisciano, SA, Italy e-mail lcavaUo unisa.it... 

Numerous studies have demonstrated that degradation products of (3-carotene exhibit deleterious effects in cellular systems (Alija et al., 2004, 2006 Hurst et al., 2005 Salerno et al., 2005 Siems et al., 2003). A mixture of (3-carotene degradation products exerts pro-apoptotic effects and cytotoxicity to human neutrophils (Salerno et al., 2005 Siems et al., 2003), and enhances the geno-toxic effects of oxidative stress in primary rat hepatocytes (Alija et al., 2004, 2006), as well as dramatically reduces mitochondrial activity in a human leukaemic cell line, K562, and RPE 28 SV4 cell line derived from stably transformed fetal human retinal pigmented epithelial cells (Hurst et al., 2005). As a result of degradation or enzymatic cleavage of (3-carotene, retinoids are formed, which are powerful modulators of cell proliferation, differentiation, and apoptosis (Blomhoff and Blomhoff, 2006). 

Salerno, C, Crifo, C, Capuozzo, E, Sommerburg, O, Langhans, CD, and Siems, W, 2005. Effect of carotenoid oxidation products on neutrophil viability and function. Biofactors 24, 185-192. 

Lattanzio V, Di Venere D, Linsalata V, Bertolini P, Ippolito A and Salerno M (2001), Low-temperature metabolism of apple phenolics and quiescence of Phyllyctaena vagabonda , J Agric Food Chem, 49, 5817-5821. 

Dipartimento di Fisica, University di Salerno, 84081 Baronissi, Salerno, Italy Table of Contents... 

Paolo CIAMBELLI Poland University of Salerno, Fisciano (SA)... 

A. L. Pankratov wishes to thank the Department of Physics E.R.Caianello of the University of Salerno, and he wishes to personally thank Professor M. Salerno for the offered position where part of this work has been done. This work has been supported by the Russian Foundation for Basic... 

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