Salbutamol sulphate

A. Salbutamol Sulphate Boron shows its presence in the above compound as a result of the use of sodium borohydride (NaBH4) in the manufacturing process. The estimation depends upon the conversion of boron to borate and the organic matter is subsequently destroyed by ignition with anhydrous sodium carbonate. The quantity of boron is finally determined by colorimetric assay. 

Materials Required Salbutamol sulphate 50 mg solution of an equimolar mixture of anhydrous sodium carbonate and potassium carbonate (3% w/v in DW) 5.0 ml Solution of curcumin (0.125% w/v in glacial acetic acid) 3.0 ml mixture of H2S04 and glacial CH3COOH (5 ml 5 ml) 3.0 ml ethanol (96%) 100 ml solution of boric acid (dissolve 5 g of boric acid in a mixture of 20 ml DW and 20 ml absolute ethanol and dilute to 250 ml with absolute ethanol) 100 ml. 

Salbutamol sulphate 0.9 g Oracet Blue-B Each ml of 0.1 N HC104 e= 0.05767 g of C13H21N03.1/2H2S04... 

Zeng XM, Martin GP, Marriott C, Pritchard J. The effects of carrier size and morphology on the dispersion of salbutamol sulphate after aerosolization at different flow rates. J Pharm Phannacol 2000 52(10) 1211-1221. 

Zeng XM, Martin GP, Tee SK, Ghoush AA, Marriott C. Effects of particle size and adding sequence of fine lactose on the deposition of salbutamol sulphate from a dry powder formulation. Int J Pharma 1999 182 133-144. 

Ticehurst MD, Rowe RC, York P. 1994. Determination of the surface properties of two batches of salbutamol sulphate by inverse gas chromatography. Int. J. Pharm. Ill ... 

Ming Zeng, X., Martin, G. P., Marriott, C., and Pritchard, J. (2001), The use of lactose recrystallised from carbopol gels as a carrier for aerosolised salbutamol sulphate, Eur. J. Pharm. Biopharm., 51,55-62. 

Sabadilla, 1061 Sabidal, 1011 Sabol, 379 Sacarina, 963 Saccarina, 963 Saccharin, 963 Saccharin calcium, 963 Saccharin sodium, 963 Saccharin, soluble, 963 Saccharoidum natricum, 963 Saffan, 329, 330 SAH, 966 Salactol, 965 Salamide, 964 Salazopyrin(e), 993 Salazosulfapyridine, 993 Salbulin, 963 Salbutamol, 963 Salbutamol sulphate, 963 Salcostat, 555 Salfuride, 813 Salicyl salicylate, 967 Salicylamide, 964 Salicylamide ethyl ether, 590... 

Pinlay, W.H. Stapleton, W.K. Zuberbuhler, P. Variations in predicted regional lung deposition of salbutamol sulphate between 19 nebulizer types. J. Aerosol Med. 1998, 11 (2), 65-80. 

Eeeley, J.C. York, P. Sumby, B.S. Dicks, H. Determination of surface properties and flow characteristics of salbutamol sulphate, before and after micronization. Int. J. Pharm. 1998, 172, 89-96. 

Tee SK, Marriott C, Zeng XM, Martin GP. Use of different sugars as fine and coarse carriers for aerosolised salbutamol sulphate. Int Pharm 2000 208 111-123. 

Finlay WH, Stapleton KW, Zuberbuhler P. Errors in regional lung deposition predictions of nebulized salbutamol sulphate due to neglect or partial inclusion of hygroscopic effects. Int J Pharm 1997 149 63-72. 

Zeng XM, Martin GP, Tee SK, Marriott C. The role of fine particle lactose on the dispersion and deaggregation of salbutamol sulphate in an air stream in vitro. Int J Pharm 1998, 176, 99 110. 

Blackett PM, Buckton G. A microcalorimetric investigation of the interaction of surfactants with crystalline and partially crystalline salbutamol sulphate in a model inhalaltion aerosol system. Pharma Res 1995 12 1689-1693. 

Feeley JC, York P, Sumby BS, Dicks H, Hanna M. In vitro assessment of salbutamol sulphate prepared by micronisation and a novel supercritical fluid technique. Drug Delivery Lungs 1998 IX 196-199. 

Richardson CH, Chrystyn H, Won ICK, Walker S. Comparison of in-vitro performance of salbutamol sulphate manufactured by a supercritical fluid process micronized salbutamol in a dry powder inhaler. AAPS PharmSci 2002 4 T3197. 

Agostini, O. Chiari, A. Ciofi Baffoni, D. Simultaneous high-performance liquid chromatographic determination of salbutamol sulphate, theophylline, and saccharin in a hydroalcoholic formulation. Boll.Chim.Farm., 1982, 121, 612-618... 

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