Safety biotechnology

Vital Safety Evaluation of Biotechnology Products Derived from CeU Liaes of Human or Animal Origin," ICH Harmonized Tripartite Guideline,... 

The current or potential iadustrial appHcations of microemulsions iaclude metal working, catalysis, advanced ceramics processiag, production of nanostmctured materials (see Nanotechnology), dyeiag, agrochemicals, cosmetics, foods, pharmaceuticals, and biotechnology (9,12—18). Environmental and human-safety aspects of surfactants have begun to receive considerable attention (19—21). 

Biotechnology. Particular attention must be paid to the detection of DNA in all finished biotechnology products because of the possibiUty that such DNA could be incorporated into the human genome and thus become a potential oncogene. The absence of DNA at the picogram-per-dose level should be demonstrated in order to assure the safety of biotechnology products (157). 

Biosafety The safety requirements necessary in biotechnology clean rooms, fume cupboards, stores, etc. 

Biotechnology Source Book Safety, Good Practice and Regulatory Affairs... 

S6 Preclinical Safety Evaluation of Biotechnology-Derived Pharmaceuticals... 

This volume benefits from the contributions of 22 outstanding scientists from the United States, Brazil, and five European countries who are well known for then-competence, sound backgrounds, and personal research experience in food science and technology and related fields such as biophysics, biochemistry, biotechnology, analytical chemistry, quality management, and food safety. 

Robertson, J. and Griffiths, E. 2001. Assuring the quality, safety and efficacy of DNA vaccines. Molecular Biotechnology 17(2), 143-149. 

ICH Topic S 6 Preclinical Safety Evaluation of Biotechnology-Derived Pharmaceuticals (CPMP/ICH/302/95). March 1998. 

Burchiel, S.W. and Weaver, J.L., Uses of Flow cytometry in preclinical safety pharmacology and toxicology, in Flow Cytometry for Biotechnology, Sklar, L.A., Ed., Oxford University Press, New York, NY, 2005, 275-290. 

Hollingworth, R.M., Bjeldanes, L.F., Bolger, M., Kimber, I., Meade, B.J., Taylor, S.L. and Wallace, K.B., Society of Toxicology position paper. The safety of genetically modified foods produced through biotechnology. Toxicol. Sci., 71,2, 2003. 

Taylor, S.L., Safety assessment of foods produced through agricultural biotechnology. Nutr. Rev., 61, S135-S140. 

Yet just as all people are not alike, neither are all food crises alike. They can vary in their familiarity, severity, proximity, consequence, and the extent to which they can be avoided. This review covers a wide range of crises from bacteria contamination, to product tampering, to fears related to irradiation and biotechnology. Different types of crises will be evaluated differently by different groups of consumers. What has been done in this review is to focus on worst-case scenarios involving initial responses to food safety issues. These will provide the most clear and illustrative profiles of consumer response. Less extreme scenarios will elicit less extreme responses. 

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