Ruthenium reaction with

Thus, Mathis et al. [1, 2] investigated oxidation reactions with 4-nitroperbenzoic acid, sodium hypobromite, osmium tetroxide and ruthenium tetroxide. Hamann et al. [3] employed phosphorus oxychloride in pyridine for dehydration. However, this method is accompanied by the disadvantages that the volume applied is increased because reagent has been added and that water is sometimes produced in the reaction and has to be removed before the chromatographic separation. 

Thermal arene exchange of tetramethylthiophene with [(/ -cymene)RuCl2]2 affords 130 (89JA8828), which on reaction with AgBE4 and excess tetramethylthiophene yields 131. The Ru—S thiophenic cluster, 132, was synthesized by reaction of 130 with (Mc3Si)2S followed by anionic metathesis and formation of the PFg salt. The coordination geometry around each ruthenium atom is pseudooctahedral. 

The main use of acrolein is to produce acrylic acid and its esters. Acrolein is also an intermediate in the synthesis of pharmaceuticals and herhicides. It may also he used to produce glycerol hy reaction with isopropanol (discussed later in this chapter). 2-Hexanedial, which could he a precursor for adipic acid and hexamethylene-diamine, may he prepared from acrolein Tail to tail dimenization of acrolein using ruthenium catalyst produces trans-2-hexanedial. The trimer, trans-6-hydroxy-5-formyl-2,7-octadienal is coproduced. Acrolein, may also he a precursor for 1,3-propanediol. Hydrolysis of acrolein produces 3-hydroxypropionalde-hyde which could he hydrogenated to 1,3-propanediol. ... 

From the reaction of 5-0-benzoyl-l,2-0-isopropylidene-o -D-en/t/iro-pentofuranos-3-ulose (prepared in 80% yield by oxidation of 5-0-benzoyl-l,2-0-isopropylidene- -D-xylofuranose (35,36) with ruthenium tetroxide) with an excess of diazomethane in methanol-ether, two main products (m.p. 44°-45°C. and 76°-77°C.), both epoxides, could be isolated by chromatography of the product on a silica column. An... 

Reaction of ruthenium red with ethylenediamine at 45°C yields a red-green analogue with chelating ethylenediamines bound to the central ruthenium [(NH3)5RuORu(en)2ORu(NH3)5]6+ (Figure 1.17). 

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