Ruta montana

Rue Oil occurs as a yellow to yellow-amber liquid with a characteristic fatty odor. It is the volatile oil obtained by steam distillation from the fresh blossoming plants Ruta graveolens L., Ruta montana L., or Ruta bracteosa L. (Fam. Rutaceae). It is soluble in most fixed oils and in mineral oil, but it is relatively insoluble in glycerin and in propylene glycol. 

Two minor alkaloids were also isolated from B. zeylanica timber. The structure of one of these, C1oN8N202, mp 223-224°C, was revised from 3,4-dihydroxy-2,2 -bipyridine (18) to 8-hydroxyquinoline-4-carbaldehyde oxime (2) based on synthetic, NMR and nuclear overhauser effect (NOE) difference NMR spectroscopic evidence (19). Natural occurrence of oximes, although rare in higher plants, is not without precedence, and the essential oil of Ruta montana L. has been reported to contain the bis-oxime of 3,4-hexanedione (20). The structure of the nonpolar minor alkaloid broussonetine, C22H16N2O4, mp 238-239°C, was elucidated as 3,4-bis(8-hydroxyquinolin-4-yl)-y-butyrolactone (4) (21). 

Vasudevan, T. N., and M. Luckner Alkaloide aus Ruta angustifolia Pers., Ruta chalepensis L., Ruta graveolens L. und Ruta montana Mill. Pharmazie 23, 520 (1968). 

Ortiz-Frutos FJ, Sanchez B, Garcia B, Iglesias L, Sanchez- 161. Mata D (1995) Photocontact dermatitis from rue (Ruta montana L.). Contact Dermatitis 33 284... 

Montanine 2,4-diOMe Aegle marmelos [38], Hortia colombiana [32], Ruta montana [24]... 

Dimethylquinolin- 1-Me, 2-Me 4(l//)-one Acronychia baueri [42], Glycosmis citrifolia [30], Platydesma campanulata [41], Ruta Montana [41]... 

Vasudevan TN, Luckner M 1968 Alkaloids from Ruta angustifolia, Ruta chalepensis, Ruta graveolens and Ruta montana. Pharmazie 23 520-521... 

An erect glaucous and nonhairy perennial herb, with a strong disagreeable odor up to about 1 m high native to the Mediterranean region cultivated worldwide (Europe, Africa, Asia, America, etc.). Part used is the dried herb. Rue oil is obtained by steam distillation of the fresh flowering plant. Ruta montana L. and R. bracteosa L. are also reported used Algerian me oil is derived from these species. 

Galipea officinalis J. Hancock (39) Ruta montana Mill, (aerial parts) (42)... 

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