Silicone rubber, sustained release

A more common contraceptive device is the intrauterine device (IUD). The first type of intrauterine device used was undedicated. These have received increased attention since the use of polyethylene plastics and silicone rubbers [194-196], These materials had the ability to resume their shape following distortion. Because they are unmedicated, these IUDs cannot be classifieds as sustained-release products. It is believed that their mechanism of action is due to local endometrial responses, both cellular and cytosecretory... 

An earlier study has Indicated the ability of parenteral prophylactic antibiotic therapy to reduce the Incidence of prosthetic mitral valve failure In dogs associated with valve related Infections. As an alternative to the above approach, we have Investigated the therapeutic efficacy of a system providing for a sustained release of gentamicin, Incorporating the antibiotic In silicone rubber which Is In the sewing rim of a mitral valve prosthesis Implanted In dogs. 

Sustained Release of Nlrldazole From Silicone Rubber... 

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