RTECS, commercial data

RTECS commercial data, 621, 749 NIR spectrophotometry see Near-infrared spectrophotometry... 

The LD q for sodium bromide taken orally by rats is 3.5 g/kg body weight, and the TD q orally in rats is 720 mg/kg (8). RTECS Hsts data on reproductive effects in male and female rats. Sodium bromide is Hsted in the TSCA Inventory, the Canadian Domestic Substances Hst (DSL), the European Inventory of Existing Commercial Chemical Substances (EINECS), the Japanese Existing and New Chemical Substances (ENCS), and the Korean Existing Chemicals Hst (ECL). It is not regulated by the U.S. Department of Transportation. 

RTECS National Institute for Occupational Safety and Health (NIOSH) registry of toxic effects of chemical substances contains toxicity data and references commercially important substances... 

CAS = Chemical Abstracts Service DOT/UN/NA/IMCO = Department of Transportation/United Nations/North America/International Maritime Dangerous Goods Code EPA = Environmental Protection Agency HSDB = Hazardous Substances Data Bank NCI = National Cancer Institute NIOSH = National Institute for Occupational Safety and Health OHMATADS = Oil and Hazardous Materials/Technical Assistance Data System RTECS = Registry of Toxic Effects of Chemical Substances STCC = Standard Transportation Commercial Code... 

The private toxicity databases offer more accurate toxicity data and the extended chemical space of representative structures in comparison with pubhc databases. Despite expansion of the chemical space and various numbers of proposed descriptors, the private databases have limitations related to the models selection, types of algorithms and the content of data, which is probably a part of confidential business information, such as a proprietary structure of pharmaceutical molecules. The private toxicity databases may also provide internal systems created by industry or government agencies [21]. These databases may not be suitable for a commercial usage, but are useful for the internal analysis. Therefore, pubhcation of the scientific research based on these data is often difficult to evaluate independently. The most known commercial databases associated with toxicity are Acceliys Toxicity Database (contains information about the structure and different types of toxicity for more than 150,000 compoimds from RTECS and other sources) and Leadscope Toxicity Database. Standardization of toxicity databases is designed to facilitate integration between different sources and to provide their quality. Since databases are often not compatible with each other, standardization initiatives (e g., controlled vocabularies) can help to combine their data [22]. 

---